Therapeutic strategies to overcome taxane resistance in cancer

T Das, U Anand, SK Pandey, CR Ashby Jr… - Drug Resistance …, 2021 - Elsevier
One of the primary causes of attenuated or loss of efficacy of cancer chemotherapy is the
emergence of multidrug resistance (MDR). Numerous studies have been published …

Natural products for cancer-targeted therapy: citrus flavonoids as potent chemopreventive agents

E Meiyanto, A Hermawan… - Asian Pacific Journal of …, 2012 - koreascience.kr
Targeted therapy has been a very promising strategy of drug development research. Many
molecular mechanims of diseases have been known to be regulated by abundance of …

Traditional uses, phytochemistry, pharmacology, toxicology and quality control of Alisma orientale (Sam.) Juzep: a review

T Tian, H Chen, YY Zhao - Journal of Ethnopharmacology, 2014 - Elsevier
Ethnopharmacological relevance Rhizoma alismatis (simplified as RA,“Zexie” in Chinese,
泽泻) is a well-known natural medicine with long history in Chinese medicine. As a …

[PDF][PDF] Cancer multidrug resistance (MDR): a major impediment to effective chemotherapy

MF Ullah - Asian Pac J Cancer Prev, 2008 - Citeseer
Multidrug resistance (MDR) continues to be a major challenge to effective chemotherapeutic
interventions against cancer. Various types of cancers have been observed to exhibit this …

Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer

W Wang, M Zhao, L Cui, Y Ren, J Zhang, J Chen, L Jia… - Molecular cancer, 2020 - Springer
Background Cisplatin is a first-line drug for the treatment of human non-small cell lung
cancer (NSCLC); however, the majority of patients will develop drug resistance after …

[图书][B] High performance liquid chromatography in phytochemical analysis

M Waksmundzka-Hajnos, J Sherma - 2010 - books.google.com
This volume is the first book to give a complete description of the techniques, materials, and
instrumentation of column HPLC and its application to essentially all primary and secondary …

P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs

T Eichhorn, T Efferth - Journal of ethnopharmacology, 2012 - Elsevier
P-glycoprotein belongs to the family of ATP-binding cassette (ABC) transporters. It functions
in cellular detoxification, pumping a wide range of xenobiotic compounds, including …

Herb–drug pharmacokinetic interactions reviewed

C Tarirai, AM Viljoen, JH Hamman - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: The global increase in the popularity of alternative medicines has
raised renewed concerns regarding herb–drug interactions. These interactions are …

Mechanism deconvolution of Qing Fei Pai Du decoction for treatment of Coronavirus Disease 2019 (COVID-19) by label-free integrative pharmacology assays

F Xu, T Hou, A Shen, H Jin, Y Xiao, W Yu, X Li… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese medicine (TCM) has a long
history in the prevention and treatment of pandemics. The TCM formula Lung Cleansing and …

Promising Anticancer Activities of Alismatis rhizome and Its Triterpenes via p38 and PI3K/Akt/mTOR Signaling Pathways

E Jang, JH Lee - Nutrients, 2021 - mdpi.com
The flowering plant genus Alisma, which belongs to the family Alismataceae, comprises 11
species, including Alisma orientale, Alisma canaliculatum, and Alisma plantago-aquatica …