An accelerated de novo lipogenesis (DNL) flux is a common characteristic of cancer cells
required to sustain a high proliferation rate. The DNL enzyme fatty acid synthase (FASN) is …

Breast cancer (BC) is one of the most common and recurring diseases and the second
leading cause of death in women. Despite prevention, diagnostics, and therapeutic options …

The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …

Curcumin, a well-known hydrophobic polyphenol extracted from the rhizomes of turmeric
(Curcuma longa L.), has attracted great interest in the last ten years due to its multiple …

Simple Summary Breast cancer remains the most commonly diagnosed cancer and the
leading cause of cancer death among females worldwide. It is a highly heterogeneous …

Worldwide breast cancer is the most common cancer in women. For many years clinicians
and the researchers are examining and exploring various therapeutic modalities for breast …

Abstract Curcumin (diferuloylmethane), an orange‑yellow component of turmeric or curry
powder, is a polyphenol natural product isolated from the rhizome of Curcuma longa. For …

Curcumin, a main bioactive component of the Curcuma longa L. rhizome, is a phenolic
compound that exerts a wide range of beneficial effects, acting as an antimicrobial …

Among the different types of breast cancers, triple-negative breast cancers (TNBCs) are
highly aggressive, do not respond to conventional hormonal/human epidermal growth factor …

Introduction: Elevated lipogenesis has been associated with a variety of diseases including
obesity, cancer and nonalcoholic fatty liver disease (NAFLD). Fatty acid synthase (FASN) …