Toxoplasma gondii causes fatal and debilitating brain and eye diseases. Medicines that are
currently used to treat toxoplasmosis commonly have toxic side effects and require …

Diaryl ether (DE) is a functional scaffold existing widely both in natural products (NPs) and
synthetic organic compounds. Statistically, DE is the second most popular and enduring …

Heterocyclic alkenes represent an important class of reactive feedstock and valuable
synthons for the synthesis of biologically important heterocyclic scaffolds. Although …

Malaria remains one of the most deadly infectious diseases globally. Considering the
growing spread of resistance, development of new and effective antimalarials remains an …

Babesiosis is an emerging tick-borne disease caused by apicomplexan parasites of the
genus Babesia. With its increasing incidence worldwide and the risk of human-to-human …

This work describes gold‐catalyzed annulations of electron‐deficient alkynes with
benzisoxazoles to yield quinoline oxides chemoselectively. Chemical functionalizations of …

Cytochrome bc 1 is a proven drug target in the prevention and treatment of malaria. The rise
in drug-resistant strains of Plasmodium falciparum, the organism responsible for malaria …

Antimalarial drug discovery has until recently been driven by high‐throughput phenotypic
cellular screening, allowing millions of compounds to be assayed and delivering clinical …

Human babesiosis is a tick-borne multisystem disease caused by Babesia species of the
apicomplexan phylum. Most clinical cases and fatalities of babesiosis are caused by …

Malaria remains a significant global health challenge due to the growing drug resistance of
Plasmodium parasites and the failure to block transmission within human host. While …