Dengue and COVID-19: two sides of the same coin

GN Malavige, C Jeewandara, GS Ogg - Journal of biomedical science, 2022 - Springer
Abstract Background Many countries in Asia and Latin America are currently facing a double
burden of outbreaks due to dengue and COVID-19. Here we discuss the similarities and …

Cell-mediated immune responses and immunopathogenesis of human tick-borne encephalitis virus-infection

K Blom, A Cuapio, JT Sandberg, R Varnaite… - Frontiers in …, 2018 - frontiersin.org
Tick-borne encephalitis virus (TBEV) is a flavivirus that belongs to the Flaviviridae family.
TBEV is transmitted to humans primarily from infected ticks. The virus causes tick-borne …

Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers

C Jeewandara, A Kamaladasa… - Nature …, 2021 - nature.com
Several COVID-19 vaccines have received emergency approval. Here we assess the
immunogenicity of a single dose of the AZD1222 vaccine, at one month, in a cohort of health …

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection

DT Wijeratne, S Fernando, L Gomes… - PLoS neglected …, 2018 - journals.plos.org
Background In order to understand the role of dengue virus (DENV) specific T cell
responses that associate with protection, we studied their frequency and phenotype in …

T-cell response to viral hemorrhagic fevers

F Perdomo-Celis, MS Salvato, S Medina-Moreno… - Vaccines, 2019 - mdpi.com
Viral hemorrhagic fevers (VHF) are a group of clinically similar diseases that can be caused
by enveloped RNA viruses primarily from the families Arenaviridae, Filoviridae …

Regulatory T‐cells in acute dengue viral infection

HE Jayaratne, D Wijeratne, S Fernando… - …, 2018 - Wiley Online Library
Although regulatory T‐cells (Tregs) have been shown to be expanded in acute dengue, their
role in pathogenesis and their relationship to clinical disease severity and extent of viraemia …

Transcriptomic immune profiles of human flavivirus‐specific T‐cell responses

A Grifoni, Y Tian, A Sette, D Weiskopf - Immunology, 2020 - Wiley Online Library
The Flavivirus genus of viruses includes dengue (DENV), Zika (ZIKV), yellow fever (YFV),
Japanese encephalitis (JEV), and West Nile (WNV) viruses. Infections with these species …

Adaptive immunity to dengue virus: slippery slope or solid ground for rational vaccine design?

L Wilken, GF Rimmelzwaan - Pathogens, 2020 - mdpi.com
The four serotypes of dengue virus are the most widespread causes of arboviral disease,
currently placing half of the human population at risk of infection. Pre-existing immunity to …

A tetravalent formulation based on recombinant nucleocapsid-like particles from dengue viruses induces a functional immune response in mice and monkeys

L Gil, K Cobas, L Lazo, E Marcos… - The Journal of …, 2016 - journals.aai.org
Despite the considerable effort that has been invested in elucidating the mechanisms of
protection and immunopathogenesis associated with dengue virus infections, a reliable …

Association of dengue virus‐specific polyfunctional T‐cell responses with clinical disease severity in acute dengue infection

DT Wijeratne, S Fernando, L Gomes… - Immunity …, 2019 - Wiley Online Library
Introduction Although the role of dengue virus (DENV)‐specific T cells in the pathogenesis of
acute dengue infection is emerging, the functionality of virus‐specific T cells associated with …