Although concussion is one of the greatest health challenges today, our physical
understanding of the cause of injury is limited. In this Letter, we simulated football head …

We have previously reported that mild TBI created by focal left-side cranial blast in mice
produces widespread axonal injury, microglial activation, and a variety of functional deficits …

Although brain, one of the most complex organs in the mammalian body, has been
subjected to many studies from physiological and pathological points of view, there remain …

Brain, the most important component of the central nervous system (CNS), is a soft tissue
with a complex structure. Understanding the role of brain tissue microstructure in mechanical …

Mild traumatic brain injury (TBI) from focal head impact is the most common form of TBI in
humans. Animal models, however, typically use direct impact to the exposed dura or skull, or …

Given the worldwide adverse impact of traumatic brain injury (TBI) on the human population,
its diagnosis and prediction are of utmost importance. Historically, many studies have …

In this study, we propose a computational characterization technique for obtaining the
material properties of axons and extracellular matrix (ECM) in human brain white matter. To …

Purpose: The purpose of this study was to examine the effect of multiple blast exposures and
blast preconditioning on the structure and function of retinal ganglion cells (RGCs), to …

Experiments have shown that shear waves induced in brain tissue can develop into shock
waves, thus providing a possible explanation of deep traumatic brain injuries. Here, we …

Motor vehicle crashes (MVC׳ s) commonly results in life threating thoracic and abdominal
injuries. Finite element models are becoming an important tool in analyzing automotive …