[HTML][HTML] Low dose ionizing radiation effects on the immune system

K Lumniczky, N Impens, G Armengol, S Candéias… - Environment …, 2021 - Elsevier
Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Radon and lung cancer: current trends and future perspectives

M Riudavets, M Garcia de Herreros, B Besse… - Cancers, 2022 - mdpi.com
Simple Summary Radon represents the main risk factor of lung cancer in non-smokers and
the second one in smoking patients. In Europe, there are several radon-prone areas, but …

Radiation effects on antitumor immune responses: current perspectives and challenges

T Walle, R Martinez Monge… - … in medical oncology, 2018 - journals.sagepub.com
Radiotherapy (RT) is currently used in more than 50% of cancer patients during the course
of their disease in the curative, adjuvant or palliative setting. RT achieves good local control …

The effect of radiation on the immune response to cancers

B Park, C Yee, KM Lee - International journal of molecular sciences, 2014 - mdpi.com
In cancer patients undergoing radiation therapy, the beneficial effects of radiation can
extend beyond direct cytotoxicity to tumor cells. Delivery of localized radiation to tumors …

Hormetic response to low-dose radiation: focus on the immune system and its clinical implications

J Cui, G Yang, Z Pan, Y Zhao, X Liang, W Li… - International journal of …, 2017 - mdpi.com
The interrelationship between ionizing radiation and the immune system is complex,
multifactorial, and dependent on radiation dose/quality and immune cell type. High-dose …

Low-dose ionizing radiation induces direct activation of natural killer cells and provides a novel approach for adoptive cellular immunotherapy

G Yang, Q Kong, G Wang, H Jin, L Zhou… - Cancer Biotherapy …, 2014 - liebertpub.com
Recent evidence indicates that limited availability and cytotoxicity have restricted the
development of natural killer (NK) cells in adoptive cellular immunotherapy (ACI). While it …

Immune recognition of irradiated cancer cells

E Wennerberg, C Vanpouille‐Box… - Immunological …, 2017 - Wiley Online Library
Ionizing irradiation has been extensively employed for the clinical management of solid
tumors, with therapeutic or palliative intents, for decades. Until recently, radiation therapy …

[HTML][HTML] The mechanobiology of NK cells-'Forcing NK to Sense'target cells

DCP Wong, JL Ding - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Natural killer (NK) cells are innate immune lymphocytes that recognize and kill cancer and
infected cells, which makes them unique 'off-the-shelf'candidates for a new generation of …

Tumor therapeutics work as stress inducers to enhance tumor sensitivity to natural killer (NK) cell cytolysis by up-regulating NKp30 ligand B7-H6

G Cao, J Wang, X Zheng, H Wei, Z Tian… - Journal of Biological …, 2015 - ASBMB
Immune cells are believed to participate in initiating anti-tumor effects during regular tumor
therapy such as chemotherapy, radiation, hyperthermia, and cytokine injection. One of the …

[HTML][HTML] Re-evaluation of the linear no-threshold (LNT) model using new paradigms and modern molecular studies

S Tharmalingam, S Sreetharan, AL Brooks… - Chemico-Biological …, 2019 - Elsevier
The linear no-threshold (LNT) model is currently used to estimate low dose radiation (LDR)
induced health risks. This model lacks safety thresholds and postulates that health risks …