Hypervalent iodine (III) compounds have found wide application in modern organic
chemistry as environmentally friendly reagents and catalysts. Hypervalent iodine reagents …

Spirocyclic molecules are widely recognized for their complex three‐dimensional features
and structural rigidity. Among this class of molecules, the spiro‐lactams subclass stands out …

Spiro-γ-lactams (spiropyrrolidin-2-ones) are a class of spirocyclic compounds that are
present in a wide range of synthetic bioactive and naturally occurring molecules. The …

In this report, we describe an alkynyl halo-aza-Prins cyclization of 3-hydroxyisoindolones to
prepare aza-Prins products. These Prins adducts undergo oxidation at the 3-isoindolone …

A visible-light photocatalytic aerobic oxidative lactonization of arene C (sp 2)–H bonds
proceeds in the presence of 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone (DDQ) and tert …

An efficient method to construct enantioenriched spiro [benzofuro-cyclopenta [1, 2-b] indole–
indoline] scaffolds via consecutive cyclization is described here. The new scaffolds possess …

The first total synthesis of antiplasmoidal isoindolinone alkaloids, spirocollequins A and B, is
described. Their diastereomeric [4.4] spirocyclic lactam core was constructed in a …

A useful oxidation of C–H bond of benzylic acetals has been achieved. This method avoids
the use of stoichiometric metals and is compatible with the presence of both electron …

New synthetic methods for spirolactams bearing an α-methylene-γ-butyrolactone or its
analogous methylene-lactam have been developed. The allylation of γ-phenylthio …