Abstract The Src-family kinases (SFKs), an intracellularly located group of non-receptor
tyrosine kinases are involved in oncogenesis. The importance of SFKs has been implicated …

Abstract Glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase is an archetypal
multifunctional moonlighting protein involved in diverse cellular processes including …

Glycogen synthase kinase 3β (GSK3β) is a multifunctional protein kinase involved in many
cellular activities including development, differentiation and diseases. GSK3β is thought to …

Growth factor-induced activation of protein kinase-B (PKB), also known as AKT, induces pro-
survival signaling and inhibits activation of pro-apoptotic signaling molecules including the …

Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide. The
association between AD and other diseases such as diabetes is well-studied. In parallel …

Glycogen synthase kinase (GSK) 3β is a multifunctional serine/threonine protein kinase with
more than 100 substrates and interacting molecules. GSK3β is normally active in cells and …

Various signaling pathways exert critical roles in the epithelial to mesenchymal transition
(EMT) and cancer stem cells (CSCs). The Wnt/beta-catenin, PI3K/PTEN/Akt/mTORC …

Decades of research have elucidated the critical role of Akt isoforms in cancer as pro-
tumorigenic and metastatic regulators through their specific effects on the cancer cells, tumor …

Retrospective studies indicate that the use of regional anesthesia can reduce cancer
recurrence after surgery which could be due to ranging from immune function preservation …

Glycogen synthase kinase 3β (GSK 3β), a multifunctional serine and threonine kinase, plays
a critical role in a variety of cellular activities, including signaling transduction, protein and …