Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

DNA can be preserved in marine and freshwater sediments both in bulk sediment and in
intact, viable resting stages. Here, we assess the potential for combined use of ancient …

Genomic alterations including single-base mutations, deletions and duplications,
translocations, mitotic recombination events, and chromosome aneuploidy generate genetic …

Mutation is the source of genetic variation and the fundament of evolution. Temperature has
long been suggested to have a direct impact on realized spontaneous mutation rates. If …

Background Elevated temperatures can cause physiological, biochemical, and molecular
responses in plants that can greatly affect their growth and development. Mutations are the …

Mutation rate and effective population size (N e) jointly determine intraspecific genetic
diversity, but the role of mutation rate is often ignored. Here we investigate genetic diversity …

Many aspects of sex chromosome evolution are common to both plants and animals [1], but
the process of Y chromosome degeneration, where genes on the Y become non-functional …

Red swamp crayfish Procambarus clarkii is an ecologically and economically important
crustacean species. Here, based on a de novo assembly strategy combining PacBio with Hi …

Loss of heterozygosity (LOH) is a mitotic recombination event that converts heterozygous
loci to homozygous loci. This mutation event is widespread in organisms that have asexual …

The rate and spectrum of spontaneous mutations are critical parameters in basic and
applied biology because they dictate the pace and character of genetic variation introduced …