Abstract Disease Overview Immunoglobulin light chain amyloidosis is a clonal,
nonproliferative plasma cell disorder in which fragments of immunoglobulin light or heavy …

Amyloid light chain (AL) amyloidosis is among the more common and more severe of the
amyloidoses usually involving the slow proliferation of a bone-marrow-residing plasma cell …

Immunoglobulin light chain (AL) amyloidosis is a clonal plasma cell disorder leading to
progressive and life-threatening organ failure. The heart and the kidneys are the most …

The term amyloidosis refers to a group of disorders in which protein fibrils accumulate in
certain organs, disrupt their tissue architecture, and impair the function of the effected organ …

High‐dose melphalan and stem cell transplantation (HDM/SCT) is an effective treatment for
selected patients with AL amyloidosis. We report the long‐term outcomes of 648 patients …

Amyloidosis is a group of disorders characterized by a misfolded protein that deposits in
organs and compromise their function. Clinician should have a high index of suspicion …

Autologous stem cell transplantation (ASCT) is considered to be the best method to achieve
deep haematological/organ responses and improve survival in selected patients with AL …

This prospective, multicenter, phase II study investigated the use of four cycles of bortezomib-
dexamethasone induction treatment, followed by high-dose melphalan and autologous stem …

Systemic amyloidosis is a heterogeneous group of diseases associated with protein
misfolding into insoluble beta-sheet rich structures that deposit extracellularly in different …

The benefits of pre-transplant induction chemotherapy in light chain (AL) amyloidosis, a low
burden plasma cell (PC) neoplasm associated with multiorgan dysfunction, is debatable …