Regulation of feeding and metabolism by neuropeptide F and short neuropeptide F in invertebrates

M Fadda, I Hasakiogullari, L Temmerman… - Frontiers in …, 2019 - frontiersin.org
Numerous neuropeptide systems have been implicated to coordinately control energy
homeostasis, both centrally and peripherally. However, the vertebrate neuropeptide Y (NPY) …

Degenerate neuronal and circuit mechanisms important for generating rhythmic motor patterns

RL Calabrese, E Marder - Physiological reviews, 2025 - journals.physiology.org
In 1996, we published a review article (Marder E, Calabrese RL. Physiol Rev 76: 687–717,
1996) describing the state of knowledge about the structure and function of the central …

[HTML][HTML] System-wide mapping of peptide-GPCR interactions in C. elegans

I Beets, S Zels, E Vandewyer, J Demeulemeester… - Cell reports, 2023 - cell.com
Neuropeptides and peptide hormones are ancient, widespread signaling molecules that
underpin almost all brain functions. They constitute a broad ligand-receptor network, mainly …

The Multilayer Connectome of Caenorhabditis elegans

B Bentley, R Branicky, CL Barnes… - PLoS computational …, 2016 - journals.plos.org
Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is
well established that extrasynaptic volume transmission, especially via monoamines and …

Sensory glia detect repulsive odorants and drive olfactory adaptation

D Duan, H Zhang, X Yue, Y Fan, Y Xue, J Shao, G Ding… - Neuron, 2020 - cell.com
Glia are typically considered as supporting cells for neural development and synaptic
transmission. Here, we report an active role of a glia in olfactory transduction. As a …

Neuromodulatory pathways in learning and memory: Lessons from invertebrates

S Van Damme, N De Fruyt, J Watteyne… - Journal of …, 2021 - Wiley Online Library
In an ever‐changing environment, animals have to continuously adapt their behaviour. The
ability to learn from experience is crucial for animals to increase their chances of survival. It …

An afferent neuropeptide system transmits mechanosensory signals triggering sensitization and arousal in C. elegans

YL Chew, Y Tanizawa, Y Cho, B Zhao, JY Alex… - Neuron, 2018 - cell.com
Sensitization is a simple form of behavioral plasticity by which an initial stimulus, often
signaling danger, leads to increased responsiveness to subsequent stimuli. Cross-modal …

Multimodal sensory processing in Caenorhabditis elegans

A Metaxakis, D Petratou, N Tavernarakis - Open biology, 2018 - royalsocietypublishing.org
Multisensory integration is a mechanism that allows organisms to simultaneously sense and
understand external stimuli from different modalities. These distinct signals are transduced …

Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans

H Jang, S Levy, SW Flavell, F Mende… - Proceedings of the …, 2017 - National Acad Sciences
A hub-and-spoke circuit of neurons connected by gap junctions controls aggregation
behavior and related behavioral responses to oxygen, pheromones, and food in …

Behavioral plasticity

Y Zhang, Y Iino, WR Schafer - Genetics, 2024 - academic.oup.com
Behavioral plasticity allows animals to modulate their behavior based on experience and
environmental conditions. Caenorhabditis elegans exhibits experience-dependent changes …