The spectrin-based membrane skeleton of the humble mammalian erythrocyte has provided
biologists with a set of interacting proteins with diverse roles in organization and survival of …

Kinesin superfamily proteins (KIFs) are key players or 'hub'proteins in the intracellular
transport system, which is essential for cellular function and morphology. The KIF …

Actin-associated proteins (AAPs) act on monomeric globular actin (G-actin) and polymerized
filamentous actin (F-actin) to regulate their dynamics and architectures which ultimately …

With the refinement of algorithms for the identification of distinct motifs from sequence
databases, especially those using secondary structure predictions, new protein modules …

This minireview will cover current concepts on the identity and mechanistic function of
smooth muscle actin binding proteins that may regulate actin-myosin interactions. The …

Smooth muscle cells possess a structural lattice composed of two primary parts: the
'cytoskeleton'that pervades the cytoplasm and the 'membrane skeleton'that provides …

Phorbol ester induces actin cytoskeleton rearrangements in cultured vascular smooth
muscle cells. Calponin and SM22 α are major components of differentiated smooth muscle …

Background: The actin-binding site of several cytoskeletal proteins is comprised of two
calponin homology (CH) domains in a tandem arrangement. As a single copy, the CH …

3544 them forming a loose triple helix bundle, and by one to three short helices present in
the loops between the core helices. Comparison of the structures of the CH domains of …

The calponin homology (CH) domain is one of the most common modules in various actin-
binding proteins and is characterized by an α-helical fold. The CH domain plays important …