MicroRNAs (miRNAs) are a class of approximately 20-nucleotides single-stranded
endogenous RNAs that regulate gene expression at the post-transcriptional level. miRNAs …

High‐mobility group box 1 (HMGB1) is originally identified as a DNA‐binding protein that
functions as a structural co‐factor critical for proper transcriptional regulation in somatic …

Cardiac biomarkers are of great importance in the timely, accurate diagnosis and
management of acute coronary syndrome as well as the prognosis. Diagnosis in the golden …

Damaged cartilage has poor self-healing ability and usually progresses to scar or
fibrocartilaginous tissue, and finally degenerates to osteoarthritis (OA). Here we …

Estimates from various disease‐specific registries suggest that chronic inflammatory and
fibrotic disorders affect a large proportion of the world's population, yet therapies for these …

Hydrogen sulfide (H2S) is a gasotransmitter which regulates multiple cardiovascular
functions. However, the precise roles of H2S in modulating myocardial fibrosis in vivo and …

Crocin is isolated from saffron and has multiple activities. There are many reports on its
beneficial effects for cardiovascular disease, but crocin's effects on anti-myocardial fibrosis …

Congestive heart failure is mostly resulted in a consequence of the limited myocardial
regeneration capacity after acute myocardial infarction. Targeted delivery of proangiogenic …

High mobility group box 1 (HMGB1) is constitutively expressed by many cells. In cells,
HMGB1 is a transcription factor or transcription enhancer that is involved in nucleosome …

Fibrosis is an accumulation of proteins including collagen in the extracellular space, which
has previously been considered as irreversible damage in various cardiovascular diseases …