Background Gastrointestinal (GI) cancers are the most common human tumors encountered
worldwide. The majority of GI cancers are unresectable at the time of diagnosis, and in the …

Cancer/testis antigens (CTAs) are named based on their expression pattern that is restricted
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …

Abstract Melanoma-associated antigens (MAGE)-A9 has been reported to play important
roles in the development of human cancers. However, the association between MAGE-A9 …

The melonoma-associated antigens family A (MAGE-A) belongs to cancer/testis antigens
(CTA) that are expressed in a wide variety of malignant tumors but not in normal adult …

MAGE proteins are cancer testis antigens (CTAs) that are characterized by highly conserved
MAGE homology domains (MHDs) and are increasingly being found to play pivotal roles in …

Cancer vaccines, including peptide-based vaccines, have been considered a key tool of
effective and protective cancer immunotherapy because of their capacity to provide long …

Digestive tract cancers, including esophageal, gastric, and colorectal cancers, are the major
cause of death among cancer patients worldwide due to the heterogeneity of cancer cells …

Purpose Esophageal cancer is a common disease in China with low survival rate due to no
obvious early symptoms and lack of effective screening strategies. Traditional treatments …

Background We attempted to identify novel biomarkers and therapeutic targets for
esophageal squamous cell carcinoma by gene expression profiling of frozen esophageal …

Background Esophageal squamous cell carcinoma (ESCC) is one of the most lethal
malignancies with poor prognosis. Cancer-testis genes (CTGs) have been vigorously …