The high selectivity and affinity of antibodies toward their antigens have made them a highly valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …
X Zhou, QR Smith, X Liu - Wiley Interdisciplinary Reviews …, 2021 - Wiley Online Library
Nearly one in six people worldwide suffer from disorders of the central nervous system (CNS). There is an urgent need for effective strategies to improve the success rates in CNS …
I Gessner, I Neundorf - International journal of molecular sciences, 2020 - mdpi.com
Based on their tunable physicochemical properties and the possibility of producing cell- specific platforms through surface modification with functional biomolecules, nanoparticles …
K Desale, K Kuche, S Jain - Biomaterials Science, 2021 - pubs.rsc.org
In the field of nanotherapeutics, gaining cellular entry into the cytoplasm of the target cell continues to be an ultimate challenge. There are many physicochemical factors such as …
Cell penetrating peptides (CPPs), also known as protein transduction domains (PTDs), first identified~ 25 years ago, are small, 6–30 amino acid long, synthetic, or naturally occurring …
JV Jun, YD Petri, LW Erickson… - Journal of the American …, 2023 - ACS Publications
We introduce a versatile strategy for the bioreversible modification of proteins. Our strategy is based on a tricomponent molecule, synthesized in three steps, that incorporates a diazo …
K Kardani, A Milani, S H. Shabani… - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …
In the last 20 years, an increasing number of studies have been reported on membrane active peptides. These peptides exert their biological activity by interacting with the cell …
The cellular transport process of DNA is hampered by cell membrane barriers, and hence, a delivery vehicle is essential for realizing the potential benefits of gene therapy to combat a …