Cell surface receptors, virus entry and tropism of primate lentiviruses

PR Clapham, Á McKnight - Journal of General Virology, 2002 - microbiologyresearch.org
Human immunodeficiency virus (HIV) exploits cell surface receptors to attach to and gain
entry into cells. The HIV envelope spike glycoprotein on the surface of virus particles binds …

Retrovirus envelope glycoproteins

E Hunter, R Swanstrom - Retroviruses: Strategies of Replication, 1990 - Springer
The envelope glycoprotein complex of replication competent retroviruses is comprised of
two polypeptides, an external, glycosylated, hydrophilic polypeptide (SU) and a membrane …

Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV

JA Hoxie, JD Alpers, JL Rackowski, K Huebner… - Science, 1986 - science.org
Cells infected with the human immunodeficiency virus (HIV) show decreased expression of
the 58-kilodalton T4 (CD4) antigen on their surface. In this study, the effect of HIV infection …

Cellular receptors and viral glycoproteins involved in retrovirus entry

RA Weiss - The retroviridae, 1993 - Springer
The initial steps in virus infection involve the binding of virions to specific cell surface
receptors. Following the attachment of enveloped viruses, further events lead to membrane …

Pathogenesis of diseases induced by human lymphotropic virus type I infection

P Hollsberg, DA Hafler - New England Journal of Medicine, 1993 - Mass Medical Soc
Although retroviruses were among the earliest viruses discovered, 1, 2 they were linked to
human disease only in the early 1980s, 3–5 with the study of T-cell lines from patients with …

Receptor interference groups of 20 retroviruses plating on human cells

MA Sommerfelt, RA Weiss - Virology, 1990 - Elsevier
The types of receptors on the surfaces of human and other mammalian cells for 13 C-type
and 7 D-type retrovirus strains were determined by interference to the formation of syncytia …

Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients

RA Weiss, PR Clapham, R Cheingsong-Popov… - Nature, 1985 - nature.com
Human T-lymphotropic virus type III (LAV, HTLV-III) 1, 2 is aetiologically linked to acquired
immune deficiency syndrome (AIDS) and persistent general lymphadenopathy (PGL) 2–7 …

Integration is not necessary for expression of human immunodeficiency virus type 1 protein products

M Stevenson, S Haggerty, CA Lamonica… - Journal of …, 1990 - Am Soc Microbiol
A common feature in the life cycle of cytocidal retroviruses, including human
immunodeficiency virus type 1 (HIV-1), is the accumulation of large amounts of unintegrated …

Envelope glycoprotein of HIV induces interference and cytolysis resistance in CD4+ cells: mechanism for persistence in AIDS

M Stevenson, C Meier, AM Mann, N Chapman… - Cell, 1988 - cell.com
Masking of host cell receptors following retroviral infection is the basis for the phenomenon
of virus interference. Amphotropic retrovirus vectors were used to express the HIV envelope …

Viruses and endogenous retroviruses as roots for neuroinflammation and neurodegenerative diseases

C Römer - Frontiers in Neuroscience, 2021 - frontiersin.org
Many neurodegenerative diseases are associated with chronic inflammation in the brain
and periphery giving rise to a continuous imbalance of immune processes. Next to …