For the longest time, the field of nucleic acid delivery has remained skeptical whether or not
polycationic drug carrier systems would ever make it into clinical practice. Yet, with the …

Self-assembly of amphiphilic polymers with hydrophilic and hydrophobic units results in
micelles (polymeric nanoparticles), where polymer concentrations are above critical micelle …

Polyelectrolyte complex micelles are hydrophilic nanoparticles that self-assemble in
aqueous environments due to associative microphase separation between oppositely …

The complexation of polyelectrolytes with other oppositely charged structures gives rise to a
great variety of functional materials with potential applications in a wide spectrum of …

The scale-up of Atom Transfer Radical Polymerization (ATRP) from 15 mL to 15 L (scale-up
factor 1000) by galvanostatic simplified electrochemically mediated ATRP (seATRP) is …

Nucleic acids are a special class of negatively charged polymers, and they can complex with
cationic small molecules and polymers to form polyelectrolyte complexes of rich …

This review article is addressed to a broad community of polymer scientists. We outline and
analyse the fundamentals of the dissipative particle dynamics (DPD) simulation method from …

Vascular disease is a leading cause of morbidity and mortality in the United States and
globally. Pathological vascular remodeling, such as atherosclerosis and stenosis, largely …

This study details the formation and characterisation of a novel nicotinamide adenine
dinucleotide (NAD+)-associated polymeric nanoparticle system. The development of a …

The using of pH-sensitive delivery systems is a promising strategy to significantly improve
the pharmacological properties of water-insoluble drugs. Herein, we propose and develop …