Heterochromatin plays a fundamental role in gene regulation, genome integrity, and
silencing of repetitive DNA elements. Histone modifications are essential for the …

Spreading of bacterial and fungal strains that are resistant to antimicrobials poses a serious
threat to the well‐being of humans, animals, and plants. Antimicrobial resistance has been …

Abstract Since the Modern Synthesis, our ideas of evolution have mostly centered on the
information encoded in the DNA molecule and their mechanisms of heredity. Increasing …

HP1 proteins are essential for establishing and maintaining transcriptionally silent
heterochromatin. They dimerize, forming a binding interface to recruit diverse chromatin …

Eukaryotic chromatin is organized into either silenced heterochromatin or relaxed
euchromatin regions, which controls the accessibility of transcriptional machinery and thus …

The 26S proteasome consists of a 20S core particle and a 19S regulatory particle and
critically regulates gene expression and silencing through both proteolytic and non …

In eukaryotes, single cells in a population display different transcriptional profiles. One of the
factors regulating this heterogeneity is the chromatin state in each cell. However, the …

In medical mycology, epigenetic mechanisms are emerging as key regulators of multiple
aspects of fungal biology ranging from development, phenotypic and morphological …

HP1 proteins bind dynamically to H3K9 methylation and are essential for establishing and
maintaining transcriptionally silent epigenetic states, known as heterochromatin. HP1 …

Epigenetic mechanisms enable cells to develop novel adaptive phenotypes without altering
their genetic blueprint. Recent studies show histone modifications, such as heterochromatin …