Plasmacytoid dendritic cell biology and its role in immune‐mediated diseases

Y Ye, B Gaugler, M Mohty… - Clinical & translational …, 2020 - Wiley Online Library
Plasmacytoid dendritic cells (pDCs) are a unique subset of dendritic cells specialised in
secreting high levels of type I interferons. pDCs play a crucial role in antiviral immunity and …

Type I interferon production of plasmacytoid dendritic cells under control

D Bencze, T Fekete, K Pázmándi - International journal of molecular …, 2021 - mdpi.com
One of the most powerful and multifaceted cytokines produced by immune cells are type I
interferons (IFNs), the basal secretion of which contributes to the maintenance of immune …

Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases

AV Skalny, TRR Lima, T Ke, JC Zhou… - Food and Chemical …, 2020 - Elsevier
Multiple medical, lifestyle, and environmental conditions, including smoking and particulate
pollution, have been considered as risk factors for COronaVIrus D isease 2019 (COVID-19) …

Cell death pathway regulation by functional nanomedicines for robust antitumor immunity

Y Li, Y Guo, K Zhang, R Zhu, X Chen… - Advanced …, 2024 - Wiley Online Library
Cancer immunotherapy has become a mainstream cancer treatment over traditional
therapeutic modes. Cancer cells can undergo programmed cell death including ferroptosis …

Arsenic as an immunotoxicant

BH Giles, KK Mann - Toxicology and Applied Pharmacology, 2022 - Elsevier
Arsenic is world-wide contaminant to which millions of people are exposed. The health
consequences of arsenic exposure are varied, including cancer, cardiometabolic disease …

Arsenic trioxide: applications, mechanisms of action, toxicity and rescue strategies to date

M Yan, H Wang, R Wei, W Li - Archives of Pharmacal Research, 2024 - Springer
Arsenical medicine has obtained its status in traditional Chinese medicine for more than
2,000 years. In the 1970s, arsenic trioxide was identified to have high efficacy and potency …

TFEB and TFE3 cooperate in regulating inorganic arsenic-induced autophagy-lysosome impairment and immuno-dysfunction in primary dendritic cells

G Xu, H Peng, R Yao, Y Yang, B Li - Cell Biology and Toxicology, 2024 - Springer
Arsenic (As) is a prevalent and hazardous environmental toxicant associated with cancer
and various health problems, which has been shown suppressive effects on dendritic cells …

Safety and efficacy of low-dose intravenous arsenic trioxide in systemic lupus erythematosus: an open-label phase IIa trial (Lupsenic)

M Hamidou, A Néel, J Poupon, Z Amoura… - Arthritis Research & …, 2021 - Springer
Background Lupus animal model has shown that arsenic trioxide (ATO), a treatment of acute
promyelocytic leukaemia, could be effective in SLE. This is the first clinical study to …

Can arsenic do anything good? Arsenic nanodrugs in the fight against cancer–last decade review

I Komorowicz, A Hanć - Talanta, 2024 - Elsevier
Arsenic has been an element of great interest among scientists for many years as it is a
widespread metalloid in our ecosystem. Arsenic is mostly recognized with negative …

[HTML][HTML] VEGFR2-targeted antibody fused with IFNαmut regulates the tumor microenvironment of colorectal cancer and exhibits potent anti-tumor and anti-metastasis …

P Shang, R Gao, Y Zhu, X Zhang, Y Wang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Although interferon α (IFNα) and anti-angiogenesis antibodies have shown appropriate
clinical benefit in the treatment of malignant cancer, they are deficient in clinical applications …