Structure comparison opens a window into the distant past of protein evolution, which has
been unreachable by sequence comparison alone. With 55000 entries in the Protein Data …

Abstract Our web site (http://ekhidna. biocenter. helsinki. fi/dali_server) runs the Dali
program for protein structure comparison. The web site consists of three parts:(i) the Dali …

Bioinformatics is inherently an innovative field that is situated at the limit of life and computer
sciences that allowed new technological advances in genome sequencing, data processing …

Abstract Our server, CLICK: http://mspc. bii. a-star. edu. sg/click, is capable of superimposing
the 3D structures of any pair of biomolecules (proteins, DNA, RNA, etc.). The server makes …

In directed evolution experiments, success often depends on the efficacy of screening or
selection methods. Genetic selections have proven to be extremely valuable for evolving …

Comparing and classifying the three-dimensional (3D) structures of proteins is of crucial
importance to molecular biology, from helping to determine the function of a protein to …

SNPs located within the open reading frame of a gene that result in an alteration in the
amino acid sequence of the encoded protein [nonsynonymous SNPs (nsSNPs)] might …

The Superimposé webserver performs structural similarity searches with a preference
towards 3D structure-based methods. Similarities can be detected between small molecules …

Background Despite the remarkable progress of bioinformatics, how the primary structure of
a protein leads to a three-dimensional fold, and in turn determines its function remains an …

Background The majority of relations between proteins can be represented as a
conventional sequential alignment. Nevertheless, unusual non-sequential alignments with …