Computational models of rhythmic motor systems are valuable tools for the study of motor
pattern generation and control. Recent modeling advances, together with experimental …

The neuropeptide, red pigment concentrating hormone (RPCH), strengthened the inhibitory
synapse from the lateral pyloric (LP) neuron to the pyloric dilator (PD) neurons in the pyloric …

Although neuromodulation of synapses is extensively documented, its consequences in the
context of network oscillations are not well known. We examine the modulation of synaptic …

A variety of neurons and synapses shows a maximal response at a preferred frequency,
generally considered to be important in shaping network activity. We are interested in …

Microcircuits in different brain areas share similar architectural and biophysical properties
with compact motor networks known as central pattern generators (CPGs). Consequently …

Rhythmic motor activity often requires neuronal output to the muscles to arrive in a particular
sequence. At the pattern-generator level, this requires distinct activity phases in different …

The phasing of neuronal activity in a rhythmic motor network is determined by a neuron's
intrinsic firing properties and synaptic inputs; these could vary in their relative importance …

The central pattern generator (CPG) for heartbeat in medicinal leeches consists of seven
identified pairs of segmental heart interneurons and one unidentified pair. Four of the …

Neuromodulators alter network output and have the potential to destabilize a circuit. The
mechanisms maintaining stability in the face of neuromodulation are not well described …

Although synaptic output is known to be modulated by changes in presynaptic calcium
channels, additional pathways for calcium entry into the presynaptic terminal, such as non …