Transcription factors (TFs) are proteins that interact with specific DNA sequences to regulate
gene expression and play crucial roles in all kinds of biological processes. To keep up with …

Abstract The Animal Transcription Factor DataBase (AnimalTFDB) is a resource aimed to
provide the most comprehensive and accurate information for animal transcription factors …

Tissue and vessel wall stiffening alters endothelial cell properties and contributes to
vascular dysfunction. However, whether extracellular matrix (ECM) stiffness impacts …

Transcription factors (TFs) and their target genes have important functions in human
diseases and biological processes. Gene expression profile analysis before and after …

Neurogenesis lasts~ 10 times longer in developing humans compared to mice, resulting in
a> 1,000-fold increase in the number of neurons in the CNS. To identify molecular and …

How cells respond to myriad stimuli with finite signaling machinery is central to immunology.
In naive T cells, the inherent effect of ligand strength on activation pathways and endpoints …

Transcription factors (TFs), transcription co-factors (TcoFs) and their target genes perform
essential functions in diseases and biological processes. KnockTF 2.0 (http://www …

Long non-coding RNAs (lncRNA), the pervasively transcribed part of the mammalian
genome, have played a significant role in changing our protein-centric view of genomes …

Transcription factors (TFs) play key roles in biological processes and are usually used as
cell markers. The emerging importance of TFs and related markers in identifying specific cell …

Compared to enhancers, silencers are notably difficult to identify and validate
experimentally. In search for human silencers, we utilized H3K27me3-DNase I …