Several transcriptional and epigenetic regulators have been functionally linked to the control
of viral and cellular gene expression programs. One such regulator is Krüppel-associated …

SARS-CoV-2 infection affects different organs and tissues, including the upper and lower
airways, the lung, the gut, the olfactory system and the eye, which may represent one of the …

The global spread of SARS-CoV-2 led to major economic and health challenges worldwide.
Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide …

SARS-CoV-2 promotes an imbalanced host response that underlies the development and
severity of COVID-19. Infections with viruses are known to modulate transposable elements …

ABSTRACT SARS-CoV-2 infection is known to trigger an important inflammatory response,
which has a major role in COVID-19 pathogenesis. In infectious and inflammatory contexts …

The human genome contains many retroviral elements called human endogenous
retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution …

In this work, we observed an increased presence of antibodies (Abs) against type I interferon
(IFN-I) in coronavirus disease 2019 (COVID-19) patients admitted to the intensive care unit …

Human endogenous retroviruses (HERVs) are 'fossil viruses' that resulted from stable
integrations of exogenous retroviruses throughout evolution. HERVs are defective and do …

Type III interferons (IFNs) play an important role in respiratory viral infections, including
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed …

Abstract Oncogene SET Domain Bifurcated 1 (SETDB1)/ESET, an H3K9 methyltransferase,
was originally discovered over two decades ago; however, its function in the immune …