Hydrogels as functional components in artificial cell systems

ME Allen, JW Hindley, DK Baxani, O Ces… - Nature Reviews …, 2022 - nature.com
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Models of Chemical Communication for Micro/Nanoparticles

J Ventura, A Llopis-Lorente… - Accounts of Chemical …, 2024 - ACS Publications
Conspectus Engineering chemical communication between micro/nanosystems (via the
exchange of chemical messengers) is receiving increasing attention from the scientific …

Transmembrane signaling by a synthetic receptor in artificial cells

AB Søgaard, AB Pedersen, KB Løvschall… - Nature …, 2023 - nature.com
Signal transduction across biological membranes is among the most important evolutionary
achievements. Herein, for the design of artificial cells, we engineer fully synthetic receptors …

Stimuli-responsive vesicles as distributed artificial organelles for bacterial activation

I Gispert, JW Hindley, CP Pilkington… - Proceedings of the …, 2022 - National Acad Sciences
Intercellular communication is a hallmark of living systems. As such, engineering artificial
cells that possess this behavior has been at the heart of activities in bottom-up synthetic …

Chemical Zymogens and Transmembrane Activation of Transcription in Synthetic Cells

DG Andersen, AB Pedersen, MH Jørgensen… - Advanced …, 2024 - Wiley Online Library
In this work, synthetic cells equipped with an artificial signaling pathway that connects an
extracellular trigger event to the activation of intracellular transcription are engineered …

Tyrosinase‐Woven Melanin Nets for Melanoma Therapy through Targeted Mitochondrial Tethering and Enhanced Photothermal Treatment

M Tang, T Duan, Y Lu, J Liu, C Gao… - Advanced …, 2024 - Wiley Online Library
Manipulating intracellular biological processes and organelles has emerged as a pivotal
strategy to influence cellular physiological functions. Mitochondria, recognized as the …

Artificial cells eavesdropping on HepG2 cells

IN Westensee, B Städler - Interface Focus, 2023 - royalsocietypublishing.org
Cellular communication is a fundamental feature to ensure the survival of cellular
assemblies, such as multicellular tissue, via coordinated adaption to changes in their …

Surpassing substrate–enzyme competition by compartmentalization

E Diamanti, D Andrés-Sanz, AH Orrego… - ACS …, 2023 - ACS Publications
Enzyme compartmentalization is one of the main strategies exploited by nature to create
physically separated chemical environments that allow simultaneous enzyme reactions …

Signal Transduction in Artificial Cells

X Yu, V Mukwaya, S Mann, H Dou - Small Methods, 2023 - Wiley Online Library
In recent years, significant progress has been made in the emerging field of constructing
biomimetic soft compartments with life‐like behaviors. Given that biological activities occur …

Competitive protein recruitment in artificial cells

TW van Veldhuisen, MAM Verwiel… - Communications …, 2024 - nature.com
Living cells can modulate their response to environmental cues by changing their
sensitivities for molecular signals. Artificial cells are promising model platforms to study …