The tumor microenvironment (TME) is the survival environment for tumor cell proliferation
and metastasis in deep tissues. Prognostic factors, such as growth, invasion and metastasis …

Expressed on virtually all prostate cancers and their metastases, the transmembrane protein
prostate-specific membrane antigen (PSMA) provides a valuable target for the imaging of …

Fibroblast activation protein (FAP), which is overexpressed in cancer-associated fibroblasts
(CAFs), represents a promising target for cancer diagnosis and therapy. Hypoxia is a …

Owing to the complex anatomical structure, precise resection of a tumor while maintaining
adjacent tissue is a challenge in radical prostatectomy for prostate cancer (PCa). Optical …

Prostate-specific membrane antigen (PSMA) imaging probes are a promising tool for the
diagnosis and image-guided surgery of prostate cancer (PCa). However, PSMA-specific …

Hypoxia plays an important role in cancer progression, which is a characteristic feature of
the tumor micro-environment and reflects the invasiveness of tumor cells. Nitroreductase …

Methods for molecular imaging of target areas, including optical imaging, radionuclide
imaging, magnetic resonance imaging and other imaging technologies, are helpful for the …

The visualization of drugs in living systems has become key techniques in modern
therapeutics. Recent advancements in optical imaging technologies and molecular design …

A novel NIR-II cyanine dye denoted as Sulfo-1100 was designed and synthesized to realize
high-fidelity in vivo imaging of orthotopic glioma. The dye in FBS (10%) and PBS showed …

Prostate cancer is one of the most frequently found cancers in men worldwide. Prostate-
specific membrane antigen (PSMA) is typically highly expressed in prostate cancer, and the …