Social isolation stress induces anxious‐depressive‐like behavior and alterations of neuroplasticity‐related genes in adult male mice

A Ieraci, A Mallei, M Popoli - Neural plasticity, 2016 - Wiley Online Library
Stress is a major risk factor in the onset of several neuropsychiatric disorders including
anxiety and depression. Although several studies have shown that social isolation stress …

Impaired GABA synthesis, uptake and release are associated with depression-like behaviors induced by chronic mild stress

K Ma, A Xu, S Cui, MR Sun, YC Xue… - Translational psychiatry, 2016 - nature.com
Major depression is a prevalent emotion disorder. Chronic stressful life in genetically
susceptible individuals is presumably a major etiology that leads to neuron and synapse …

[HTML][HTML] Searching basic units in memory traces: associative memory cells

JH Wang - F1000Research, 2019 - ncbi.nlm.nih.gov
The acquisition of associated signals is commonly seen in life. The integrative storage of
these exogenous and endogenous signals is essential for cognition, emotion and behaviors …

Negative affect and excessive alcohol intake incubate during protracted withdrawal from binge-drinking in adolescent, but not adult, mice

KM Lee, MA Coehlo, NR Solton… - Frontiers in …, 2017 - frontiersin.org
Binge-drinking is common in underage alcohol users, yet we know little regarding the
biopsychological impact of binge-drinking during early periods of development. Prior work …

[HTML][HTML] GABAergic neurons in nucleus accumbens are correlated to resilience and vulnerability to chronic stress for major depression

Z Zhu, G Wang, K Ma, S Cui, JH Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Major depression, persistent low mood, is one of common psychiatric diseases.
Chronic stressful life is believed to be a major risk factor that leads to dysfunctions of the …

microRNA and mRNA profiles in the amygdala are associated with stress-induced depression and resilience in juvenile mice

M Shen, Z Song, JH Wang - Psychopharmacology, 2019 - Springer
Objectives Major depressive disorder characterized as recurrent negative mood is one of the
prevalent psychiatric diseases. Chronic stress plus lack of reward may induce long-term …

Neurons in the barrel cortex turn into processing whisker and odor signals: a cellular mechanism for the storage and retrieval of associative signals

D Wang, J Zhao, Z Gao, N Chen, B Wen… - Frontiers in Cellular …, 2015 - frontiersin.org
Associative learning and memory are essential to logical thinking and cognition. How the
neurons are recruited as associative memory cells to encode multiple input signals for their …

Incoordination among subcellular compartments is associated with depression-like behavior induced by chronic mild stress

A Xu, S Cui, JH Wang - International Journal of …, 2016 - academic.oup.com
Background: Major depressive disorder is characterized as persistent low mood. A
chronically stressful life in genetically susceptible individuals is presumably the major …

[HTML][HTML] mRNA and miRNA profiles in the nucleus accumbens are related to fear memory and anxiety induced by physical or psychological stress

K Du, W Lu, Y Sun, J Feng, JH Wang - Journal of psychiatric research, 2019 - Elsevier
Anxiety is presumably driven by fear memory. The nucleus accumbens involves emotional
regulation. Molecular profiles in the nucleus accumbens related to stress-induced fear …

Associations of unilateral whisker and olfactory signals induce synapse formation and memory cell recruitment in bilateral barrel cortices: cellular mechanism for …

Z Gao, L Chen, R Fan, W Lu, D Wang, S Cui… - Frontiers in Cellular …, 2016 - frontiersin.org
Somatosensory signals and operative skills learned by unilateral limbs can be retrieved
bilaterally. In terms of cellular mechanism underlying this unilateral learning toward bilateral …