Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …

Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

Despite significant advances in the fabrication of bioengineered scaffolds for tissue
engineering, delivery of nutrients in complex engineered human tissues remains a …

Photocrosslinkable materials have been frequently used for constructing soft and biomimetic
hydrogels for tissue engineering. Although ultraviolet (UV) light is commonly used for …

The relationship between ECM mechanics and cell behavior is dynamic, as cells remodel
and respond to changes in their local environment. Most in vitro substrates are static and …

In the past decade, substantial evidence supports the paradigm that stem cells exert their
reparative and regenerative effects, in large part, through the release of biologically active …

Decellularized extracellular matrix (dECM) is a promising biomaterial for repairing
cardiovascular tissue, as dECM most effectively captures the complex array of proteins …

Cardiac fibrosis is a serious condition currently lacking effective treatments. It occurs as a
result of cardiac fibroblast (CFB) activation and differentiation into myofibroblasts …

Mesenchymal stem cells have been used for cardiovascular regenerative therapy for
decades. These cells have been established as one of the potential therapeutic agents …

Rationale: Cardiac ECM (extracellular matrix) comprises a dynamic molecular network
providing structural support to heart tissue function. Understanding the impact of ECM …