The on‐again, off‐again relationship between mitochondrial genomes and species boundaries
The study of reproductive isolation and species barriers frequently focuses on mitochondrial
genomes and has produced two alternative and almost diametrically opposed narratives. On …
genomes and has produced two alternative and almost diametrically opposed narratives. On …
Assessing the fitness consequences of mitonuclear interactions in natural populations
Metazoans exist only with a continuous and rich supply of chemical energy from oxidative
phosphorylation in mitochondria. The oxidative phosphorylation machinery that mediates …
phosphorylation in mitochondria. The oxidative phosphorylation machinery that mediates …
Mitochondrial pathways in human health and aging
R Bornstein, B Gonzalez, SC Johnson - Mitochondrion, 2020 - Elsevier
Mitochondria are eukaryotic organelles known best for their roles in energy production and
metabolism. While often thought of as simply the 'powerhouse of the cell,'these organelles …
metabolism. While often thought of as simply the 'powerhouse of the cell,'these organelles …
Investigating mitonuclear interactions in human admixed populations
To function properly, mitochondria utilize products of 37 mitochondrial and> 1,000 nuclear
genes, which should be compatible with each other. Discordance between mitochondrial …
genes, which should be compatible with each other. Discordance between mitochondrial …
Efficiency of mitochondrial functioning as the fundamental biological mechanism of general intelligence (g).
DC Geary - Psychological Review, 2018 - psycnet.apa.org
General intelligence or g is one of the most thoroughly studied concepts in the behavioral
sciences. Measures of intelligence are predictive of a wide range of educational …
sciences. Measures of intelligence are predictive of a wide range of educational …
Mitochondrial genetics
VF Gonçalves - Mitochondria in Health and in Sickness, 2019 - Springer
The maternally inherited mitochondrial DNA (mtDNA) is located inside every mitochondrion,
in variable number of copies, and it contains 37 crucial genes for cellular bioenergetics. This …
in variable number of copies, and it contains 37 crucial genes for cellular bioenergetics. This …
Mitochondrial replacement therapy: are mito-nuclear interactions likely to be a problem?
A Eyre-Walker - Genetics, 2017 - academic.oup.com
It has been suggested that deleterious interactions between the mitochondrial and nuclear
genomes could pose a problem for mitochondrial replacement therapy (MRT). This is …
genomes could pose a problem for mitochondrial replacement therapy (MRT). This is …
Integrative approaches for studying mitochondrial and nuclear genome co-evolution in oxidative phosphorylation
In animals, interactions among gene products of mitochondrial and nuclear genomes
(mitonuclear interactions) are of profound fitness, evolutionary, and ecological significance …
(mitonuclear interactions) are of profound fitness, evolutionary, and ecological significance …
[HTML][HTML] Evolutionary codependency: insights into the mitonuclear interaction landscape from experimental and wild Caenorhabditis nematodes
Highlights•Caenorhabditis are versatile models for mitonuclear coevolution research.•C.
elegans mitochondrial DNA mutation spectra may reflect oxidative DNA damage.• …
elegans mitochondrial DNA mutation spectra may reflect oxidative DNA damage.• …
Novel complex interactions between mitochondrial and nuclear DNA in schizophrenia and bipolar disorder
A Schulmann, E Ryu, V Goncalves, B Rollins… - Complex …, 2019 - karger.com
Mitochondrial dysfunction has been associated with schizophrenia (SZ) and bipolar disorder
(BD). This review examines recent publications and novel associations between …
(BD). This review examines recent publications and novel associations between …