Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …

The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …

Plasticity of cancer invasion and metastasis depends on the ability of cancer cells to switch
between collective and single-cell dissemination, controlled by cadherin-mediated cell–cell …

Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Time-lapse, deep-tissue imaging made possible by advances in intravital microscopy has
demonstrated the importance of tumour cell migration through confining tracks in vivo. These …

The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …

Activity and autonomous motion are fundamental in living and engineering systems. This
has stimulated the new field of'active matter'in recent years, which focuses on the physical …

Actomyosin machinery endows cells with contractility at a single-cell level. However, within a
monolayer, cells can be contractile or extensile based on the direction of pushing or pulling …

Steady-state turnover is a hallmark of epithelial tissues throughout adult life. Intestinal
epithelial turnover is marked by continuous cell migration, which is assumed to be driven by …