When cells undergo necrotic cell death in either physiological or pathophysiological settings
in vivo, they release highly immunogenic intracellular molecules and organelles into the …

Upon solid organ transplantation and during cancer immunotherapy, cellular stress
responses result in the release of damage-associated molecular patterns (DAMPs). The …

Background Brain death (BD) has been suggested to induce coronary endothelial
dysfunction. Ischemia/reperfusion (IR) injury during heart transplantation may lead to further …

The study was conducted to compare effects of different dietary Se sources (sodium selenite
[NaSe], Se-enriched yeast [Se yeast] or L-selenomethionine [SeMet]) and one Se-deficient …

The importance of the complement system in renal ischemia-reperfusion injury and acute
rejection is widely recognized, however its contribution to the pathogenesis of tissue …

The eIF5A hypusination inhibitor GC7 (N1-guanyl-1, 7-diaminoheptane) was shown to
protect from ischemic injuries. We hypothesized that GC7 could be useful for preconditioning …

Background Prolactin (PRL) has been reported to be associated with oxidative stress, which
is an important contributor leading to cell apoptosis. However, little is known about the …

Many factors during the transplantation process influence posttransplant graft function and
survival, including donor type and age, graft preservation methods (cold storage, machine …

Background Children with congenital heart disease are often operated at a very young age.
Cardiopulmonary bypass (CPB) has become indispensable for these sometimes very …

Ischemia reperfusion injury is one of the major complications responsible for delayed graft
function in kidney transplantation. Applications to reduce reperfusion injury are essential …