Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021 - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

An acidity‐unlocked magnetic nanoplatform enables self‐boosting ROS generation through upregulation of lactate for imaging‐guided highly specific chemodynamic …

L Shi, Y Wang, C Zhang, Y Zhao, C Lu… - Angewandte …, 2021 - Wiley Online Library
Chemodynamic therapy is an emerging tumor therapeutic strategy. However, the anticancer
effects are greatly limited by the strong acidity requirements for effective Fenton‐like …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Small molecular NIR-II fluorophores for cancer phototheranostics

H Dai, Q Shen, J Shao, W Wang, F Gao, X Dong - The Innovation, 2021 - cell.com
Phototheranostics integrates deep-tissue imaging with phototherapy (containing
photothermal therapy and photodynamic therapy), holding great promise in early diagnosis …

Design, synthesis, and application of a small molecular NIR-II fluorophore with maximal emission beyond 1200 nm

Y Fang, J Shang, D Liu, W Shi, X Li… - Journal of the American …, 2020 - ACS Publications
Small molecular fluorophores in the second near-infrared window (NIR-II) have aroused
much interest because of their excellent performance. Herein, a new small molecular NIR-II …

A general approach to design dual ratiometric fluorescent and photoacoustic probes for quantitatively visualizing tumor hypoxia levels in vivo

S Zhang, H Chen, L Wang, X Qin, BP Jiang… - Angewandte …, 2022 - Wiley Online Library
Herein, we describe an energy balance strategy between fluorescence and photoacoustic
effects by sulfur substitution to transform existing hemicyanine dyes (Cy) into optimized …

Recent progress on molecularly near-infrared fluorescent probes for chemotherapy and phototherapy

C Yan, Y Zhang, Z Guo - Coordination Chemistry Reviews, 2021 - Elsevier
Recently, molecularly fluorophores for nanotheranostics, bridging in vivo imaging and
therapeutic capability within unimolecular system, has attracted increasing attention …

Recent development of pH‐responsive theranostic nanoplatforms for magnetic resonance imaging‐guided cancer therapy

X Li, R Yue, G Guan, C Zhang, Y Zhou, G Song - Exploration, 2023 - Wiley Online Library
The acidic characteristic of the tumor site is one of the most well‐known features and
provides a series of opportunities for cancer‐specific theranostic strategies. In this regard …

Mitochondria‐targeting phototheranostics by aggregation‐induced NIR‐II emission luminogens: modulating intramolecular motion by electron acceptor engineering …

T Zhang, J Zhang, FB Wang, H Cao… - Advanced Functional …, 2022 - Wiley Online Library
Phototheranostic agents have thrived as promising tools for cancer theranostics because of
the integration of sensitive in situ fluorescence imaging and effective multi‐model synergistic …