Prospects for the convergence of polyphenols with pharmaceutical drugs in type 2 diabetes: Challenges, risks, and strategies

S Allamreddy, M Arora, R Ganugula, R Friend… - Pharmacological …, 2025 - Elsevier
Type 2 diabetes mellitus (T2DM) is a complex disease that can lead to a variety of life-
threatening secondary health conditions. Current treatment strategies primarily revolve …

From conventional to cutting-edge: Exosomes revolutionizing nano-drug delivery systems

H Fu, Y Chen, Q Fu, Q Lv, J Zhang, Y Yang… - Chemical Engineering …, 2024 - Elsevier
To address challenges encountered by conventional drug delivery systems (DDS) such as
easy degradation, poor utilization, and low loading rates, researchers have been …

Intranasal bilosomes in thermosensitive hydrogel: advancing desvenlafaxine succinate delivery for depression management

TM El-Nawawy, YA Adel, M Teaima… - Pharmaceutical …, 2024 - Taylor & Francis
Depression, the second biggest cause of disability worldwide, is widespread. Many
antidepressant medications, including Desvenlafaxine Succinate (DVS), function by …

A resveratrol based active ester cured epoxy film with low dielectric loss and high thermal performances

Z Zhao, X Wang, J Tian, Y Gao, F Chen, S Li… - Progress in Organic …, 2023 - Elsevier
The production of epoxy resins with low dissipation factor (D f) remains an alluring yet
challenging task. In this work, we successfully synthesized a novel resveratrol based active …

Repaglinide–Solid Lipid Nanoparticles in Chitosan Patches for Transdermal Application: Box–Behnken Design, Characterization, and In Vivo Evaluation

HSM Ali, N Namazi, HM Elbadawy… - International Journal …, 2024 - Taylor & Francis
Background Repaglinide (REP) is an antidiabetic drug with limited oral bioavailability
attributable to its low solubility and considerable first-pass hepatic breakdown. This study …

Novel inhalable nano-based/microparticles for enhanced sustained pulmonary delivery of remdesivir-A patient malleable treatment for coronaviruses infection: In vitro …

SA Fouad, FA Malaak, MH Teaima, S Omar… - Journal of Drug Delivery …, 2024 - Elsevier
Remdesivir (RDV) is an antiviral used in potential treatment of SARS-COV-2 infection during
the COVID-19 pandemic worldwide. However, it is still limited to IV administration for …

Transdermal fluocinolone acetonide loaded decorated hyalurosomes cellulose acetate/polycaprolactone nanofibers mitigated Freund's adjuvant-induced rheumatoid …

SF ELhabal, MA El-Nabarawi, SO Hassanin… - Journal of …, 2024 - Springer
Purpose This study aimed to develop a transdermal delivery system for fluocinolone
acetonide (FLA), a corticosteroid used in treating inflammatory conditions like rheumatoid …

New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in …

SA Fouad, TA Badr, A Abdelbary, M Fadel… - AAPS …, 2024 - Springer
Cellulite (CLT) is one of the commonly known lipodystrophy syndromes affecting post-
adolescent women worldwide. It is topographically characterized by an orange-peel …

Revolutionizing Psoriasis Topical Treatment: Enhanced Efficacy Through Ceramide/Phospholipid Composite Cerosomes Co-Delivery of Cyclosporine and Dithranol …

SF Elhabal, N Abdelaal, SAS Al-Zuhairy… - International Journal …, 2024 - Taylor & Francis
Purpose Improving the treatment of psoriasis is a serious challenge today. Psoriasis is an
immune-mediated skin condition affecting 125 million people worldwide. It is commonly …

Exploring innovative approaches in type-2 diabetes management: a comprehensive review on nano-carriers and transdermal drug delivery

N Chauhan, M Kumar, K Kumar… - Current …, 2024 - benthamdirect.com
Diabetes is a chronic metabolic disorder characterized by elevated blood sugar levels and
encompasses various types like type 1, type 2, gestational, and prediabetes. This review …