[HTML][HTML] Genetics of amino acid taste and appetite

AA Bachmanov, NP Bosak, JI Glendinning, M Inoue… - Advances in …, 2016 - Elsevier
The consumption of amino acids by animals is controlled by both oral and postoral
mechanisms. We used a genetic approach to investigate these mechanisms. Our studies …

Sweet Taste Receptors and Associated Sweet Peptides: Insights into Structure and Function

S Zhao, H Zheng, Y Lu, N Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Long-term consumption of a high-sugar diet may contribute to the pathogenesis of several
chronic diseases, such as obesity and type 2 diabetes. Sweet peptides derived from a wide …

Comprehensive analysis of mouse bitter taste receptors reveals different molecular receptive ranges for orthologous receptors in mice and humans

K Lossow, S Hübner, N Roudnitzky, JP Slack… - Journal of Biological …, 2016 - ASBMB
One key to animal survival is the detection and avoidance of potentially harmful compounds
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory …

Modulation of taste sensitivity by GLP‐1 signaling

YK Shin, B Martin, E Golden, CD Dotson… - Journal of …, 2008 - Wiley Online Library
In many sensory systems, stimulus sensitivity is dynamically modulated through
mechanisms of peripheral adaptation, efferent input, or hormonal action. In this way …

Nutrient selection in the absence of taste receptor signaling

X Ren, JG Ferreira, L Zhou… - Journal of …, 2010 - Soc Neuroscience
When allowed to choose between different macronutrients, most animals display a strong
attraction toward carbohydrates compared with proteins. It remains uncertain, however …

T1R3 taste receptor is critical for sucrose but not Polycose taste

S Zukerman, JI Glendinning… - American Journal …, 2009 - journals.physiology.org
In addition to their well-known preference for sugars, mice and rats avidly consume starch-
derived glucose polymers (eg, Polycose). T1R3 is a component of the mammalian sweet …

Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants

YK Shin, B Martin, W Kim, CM White, S Ji, Y Sun… - PloS one, 2010 - journals.plos.org
Background The gustatory system plays a critical role in determining food preferences, food
intake and energy balance. The exact mechanisms that fine tune taste sensitivity are …

Genetics of sweet taste preferences

AA Bachmanov, NP Bosak, WB Floriano… - Flavour and …, 2011 - Wiley Online Library
Sweet taste is a powerful factor influencing food acceptance. There is considerable variation
in sweet taste perception and preferences within and among species. Although learning and …

Vasoactive intestinal peptide–null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud Leptin receptor expression

B Martin, YK Shin, CM White, S Ji, W Kim… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE It is becoming apparent that there is a strong link between taste perception and
energy homeostasis. Recent evidence implicates gut-related hormones in taste perception …

The functional role of the T1R family of receptors in sweet taste and feeding

Y Treesukosol, KR Smith, AC Spector - Physiology & behavior, 2011 - Elsevier
The discovery of the T1R family of Class CG protein-coupled receptors in the peripheral
gustatory system a decade ago has been a tremendous advance for taste research, and its …