Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms
ER Drury, J Wu, JC Gigliotti, TH Le - Physiological Reviews, 2024 - journals.physiology.org
The teleology of sex differences has been argued since at least as early as Aristotle's
controversial Generation of Animals more than 300 years BC, which reflects the sex bias of …
controversial Generation of Animals more than 300 years BC, which reflects the sex bias of …
Guidelines on the use of sex and gender in cardiovascular research
CW Usselman, ML Lindsey… - American Journal …, 2024 - journals.physiology.org
In cardiovascular research, sex and gender have not typically been considered in research
design and reporting until recently. This has resulted in clinical research findings from which …
design and reporting until recently. This has resulted in clinical research findings from which …
Aerobic exercise training reduces ET-1-mediated vasoconstriction and improves endothelium-dependent vasodilation in postmenopausal women
Endothelin-1 (ET-1) contributes to vascular dysfunction in postmenopausal women (PMW).
Although aerobic exercise is beneficial in reducing ET-1-mediated vasoconstrictor tone in …
Although aerobic exercise is beneficial in reducing ET-1-mediated vasoconstrictor tone in …
Mechanism of action of topical tranexamic acid in the treatment of melasma and sun-induced skin hyperpigmentation
K Maeda - Cosmetics, 2022 - mdpi.com
Tranexamic acid (TXA) has anti-plasmin activity and has been shown when administered
orally to be effective against melasma, for which it is considered first-line pharmacotherapy …
orally to be effective against melasma, for which it is considered first-line pharmacotherapy …
Estrogen receptor subtype mediated anti-inflammation and vasorelaxation via genomic and nongenomic actions in septic mice
L Zhang, H Wan, M Zhang, W Lu, F Xu… - Frontiers in …, 2023 - frontiersin.org
Aim Sepsis is a life-threatening disease with high mortality worldwide. Septic females have
lower severity and mortality than the males, suggesting estrogen exerts a protective action …
lower severity and mortality than the males, suggesting estrogen exerts a protective action …
The effect of endothelin a receptor inhibition and biological sex on cutaneous microvascular function in non‐Hispanic Black and White young adults
The purpose of this study was to investigate whether endothelin‐A receptor (ETAR)
inhibition in non‐Hispanic Black (NHB) and White (NHW) young adults depends on …
inhibition in non‐Hispanic Black (NHB) and White (NHW) young adults depends on …
Galanin receptors modulate cutaneous vasodilation elicited by whole-body and local heating but not thermal sweating in young adults
N Fujii, R Rakwal, J Shibato, Y Tanabe… - European Journal of …, 2023 - Elsevier
Galanin receptor subtypes GAL 1, GAL 2, and GAL 3 are involved in several biological
functions. We hypothesized that 1) GAL 3 receptor activation contributes to sweating but …
functions. We hypothesized that 1) GAL 3 receptor activation contributes to sweating but …
Endothelin A receptor inhibition increases nitric oxide-dependent vasodilation independent of superoxide in non-Hispanic Black young adults
Young non-Hispanic Black adults have reduced microvascular endothelial function
compared with non-Hispanic White counterparts, but the mechanisms are not fully …
compared with non-Hispanic White counterparts, but the mechanisms are not fully …
TMEM16A blockers T16Ainh‐A01 and benzbromarone do not modulate the regulation of sweating and cutaneous vasodilatation in humans in vivo
New Findings What is the central question of this study? Do transmembrane member 16A
(TMEM16A) blockers modulate the activation of heat loss responses of sweating and …
(TMEM16A) blockers modulate the activation of heat loss responses of sweating and …
Comprehensive analysis of the endothelin system in the kidneys of mice, rats, and humans
The intrarenal endothelin (ET) system is an established moderator of kidney physiology and
mechanistic contributor to the pathophysiology and progression of chronic kidney disease in …
mechanistic contributor to the pathophysiology and progression of chronic kidney disease in …