Helicobacter pylori and gastrointestinal tract adenocarcinomas

RM Peek Jr, MJ Blaser - Nature Reviews Cancer, 2002 - nature.com
Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

[HTML][HTML] Helicobacter pylori persistence: biology and disease

MJ Blaser, JC Atherton - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from
person to person and to persistently colonize the stomach. Their population structure is a …

Helicobacter pylori and Its Role in Gastric Cancer

VE Reyes - Microorganisms, 2023 - mdpi.com
Gastric cancer is a challenging public health concern worldwide and remains a leading
cause of cancer-related mortality. The primary risk factor implicated in gastric cancer …

[HTML][HTML] Effect of Helicobacter pylori on gastric epithelial cells

S Alzahrani, TT Lina, J Gonzalez… - World journal of …, 2014 - ncbi.nlm.nih.gov
The gastrointestinal epithelium has cells with features that make them a powerful line of
defense in innate mucosal immunity. Features that allow gastrointestinal epithelial cells to …

The induction of apoptosis by bacterial pathogens

Y Weinrauch, A Zychlinsky - Annual Reviews in Microbiology, 1999 - annualreviews.org
▪ Abstract Apoptosis is a highly regulated process of cell death that is required for the
development and homeostasis of multicellular organisms. In contrast to necrosis, apoptosis …

Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-γ, gene-deficient mice

LE Smythies, KB Waites, JR Lindsey… - The Journal of …, 2000 - journals.aai.org
To elucidate the pathogenesis of Helicobacter pylori-associated gastritis, we studied
immune responses of C57BL/6J wild-type (WT), SCID, and gene deficient (IFN-γ−/− and IL …

Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies

KT Wilson, JE Crabtree - Gastroenterology, 2007 - Elsevier
Helicobacter pylori infects the stomach of half of the human population worldwide and
causes chronic active gastritis, which can lead to peptic ulcer disease, gastric …

Apoptosis in the intestinal epithelium: its relevance in normal and pathophysiological conditions

A Ramachandran, M Madesh… - Journal of …, 2000 - Wiley Online Library
Apoptosis is now recognized as an important process responsible for maintenance of the
cellular balance between proliferation and death. Apoptosis is distinct from necrosis in that it …

Apoptosis in gastric epithelium induced byHelicobacter pyloriinfection: implications in gastric carcinogenesis

HHX Xia, NJ Talley - Official journal of the American College of …, 2001 - journals.lww.com
OBJECTIVES: Helicobacter pylori is an identified carcinogen for gastric cancer, however, the
underlying mechanisms remain to be defined. In this review, we sought to elucidate the role …

Favourable effect of an acidified milk (LC-1) on Helicobacter pylori gastritis in man

CP Felley, I Corthésy-Theulaz, JLB Rivero… - European journal of …, 2001 - journals.lww.com
Objective The supernatant of Lactobacillus johnsonii La1 culture was shown to be
bactericidal and to have a partial, acid-independent suppressive effect on Helicobacter …