RGS proteins and their roles in cancer: friend or foe?

L Li, Q Xu, C Tang - Cancer Cell International, 2023 - Springer
As negative modulators of G-protein-coupled receptors (GPCRs) signaling, regulators of G
protein signaling (RGS) proteins facilitate various downstream cellular signalings through …

Regulating the regulators: Epigenetic, transcriptional, and post-translational regulation of RGS proteins

M Alqinyah, SB Hooks - Cellular signalling, 2018 - Elsevier
Regulators of G protein signaling (RGS) are a family of proteins classically known to
accelerate the intrinsic GTPase activity of G proteins, which results in accelerated …

[HTML][HTML] The Role of MicroRNAs in the Pathogenesis of Doxorubicin-Induced Vascular Remodeling

E Podyacheva, J Snezhkova, A Onopchenko… - International Journal of …, 2024 - mdpi.com
Doxorubicin (DOX), a cornerstone chemotherapeutic agent, effectively combats various
malignancies but is marred by significant cardiovascular toxicity, including endothelial …

Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone

I Mohanty, J Singh, S Rattan - Scientific reports, 2019 - nature.com
Aging-associated decrease in internal anal sphincter (IAS) tone (AADI) is a major contributor
in the rectoanal incontinence (RI). To determine the pathogenesis of AADI, we investigated …

Association Analysis Between SNPs in the Promoter Region of RGS4 and Schizophrenia in the Northern Chinese Han Population

F Xu, J Yao, X Wu, X Xia, J Xing, J Xuan… - Neuropsychiatric …, 2020 - Taylor & Francis
Background Abnormal RGS4 gene expression may cause neurotransmitter disorders,
resulting in schizophrenia. The association between RGS4 and the risk of schizophrenia is …

Deep sequencing of the mouse lung transcriptome reveals distinct long non-coding RNAs expression associated with the high virulence of H5N1 avian influenza virus …

J Hu, Z Hu, X Wang, M Gu, Z Gao, Y Liang, C Ma, X Liu… - Virulence, 2018 - Taylor & Francis
Long non-coding RNAs (lncRNAs) play multiple key regulatory roles in various biological
processes. However, their function in influenza A virus (IAV) pathogenicity remains largely …

The transcriptional factor GATA-4 negatively regulates Hsp70 transcription in Crassostrea hongkongensis

T Hou, D Xu, M Cui, H Liu, Y Fu, L Zhang… - Molecular Biology …, 2020 - Springer
To better explore the application potential of heat shock protein Hsp70s in diverse areas
including biomonitoring, a further investigation of the details of the regulatory mechanism …