An epigenetic synopsis of parental substance use

JO Lo, RJ D'Mello, L Watch, DJ Schust, SK Murphy - Epigenomics, 2023 - Taylor & Francis
The rate of substance use is rising, especially among reproductive-age individuals.
Emerging evidence suggests that paternal pre-conception and maternal prenatal substance …

Influence of substance use on male reproductive health and offspring outcomes

JO Lo, JC Hedges, WH Chou, KR Tager… - Nature Reviews …, 2024 - nature.com
The prevalence of substance use globally is rising and is highest among men of
reproductive age. In Africa, and South and Central America, cannabis use disorder is most …

Temporal Trends in Semen Quality, Hormone Levels, and Substance Use Among Infertile Men in Pre-and Post-Cannabis Legalization Eras in Canada

G Karavani, A Bobrowski, K Lajkosz, S Lau… - Cannabis and …, 2024 - liebertpub.com
Background: The Cannabis Act (Bill C-45) was enacted in 2018, to legalize and regulate the
use, production, and sale of nonmedical cannabis in Canada. While public health and safety …

Partial reversal of chronic delta-9-tetrahydrocannabinol-induced effects on male fertility and sperm epigenome after cessation

Y Valdes, V Giraldo, J Eisermann, H Arora - Fertility and sterility, 2023 - fertstert.org
Cannabis represents the most prevalent substance used among men in their reproductive
years; nevertheless, research on the impact of chronic cannabis consumption on male …