Breast cancer is the second leading cause of cancer deaths among women. The
development of breast cancer is a multi-step process involving multiple cell types, and its …

Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …

RNA-binding proteins (RBPs) are critical regulators of post-transcriptional gene expression,
and aberrant RBP-RNA interactions can promote cancer progression. Here, we interrogate …

Triple-negative breast cancer (TNBC) is an aggressive breast type of cancer with no
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …

Driver mutations in oncogenic pathways, rewiring of cellular metabolism and altered ROS
homoeostasis are intimately connected hallmarks of cancer. Electrons derived from different …

Endocrine therapy resistance frequently develops in estrogen receptor positive (ER+) breast
cancer, but the underlying molecular mechanisms are largely unknown. Here, we show that …

Abstract Background Glutamine (Gln) is an abundant nutrient used by cancer cells. Breast
cancers cells and particularly triple-receptor negative breast cancer (TNBC) are reported to …

Extensive research efforts have been made and are still ongoing in the search for an ideal
anti-cancer therapy. Almost all chemotherapeutics require a carrier or vehicle, a drug …

The past few decades have witnessed a tremendous progress in understanding the biology
of cancer, which has led to more comprehensive approaches for global gene expression …

Background Breast cancer (BC) is a heterogeneous disease characterised by variant
biology and patient outcome. The amino acid transporter, SLC7A5, plays a role in BC …