Salivary biomarkers: novel noninvasive tools to diagnose chronic inflammation
Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …
MicroRNA profiling: approaches and considerations
CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …
thousands of genes in a broad range of organisms in both normal physiological contexts …
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA
L Zhang, D Hou, X Chen, D Li, L Zhu, Y Zhang, J Li… - Cell research, 2012 - nature.com
Our previous studies have demonstrated that stable microRNAs (miRNAs) in mammalian
serum and plasma are actively secreted from tissues and cells and can serve as a novel …
serum and plasma are actively secreted from tissues and cells and can serve as a novel …
MicroRNA signatures in human cancers
MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …
cancer. The causes of the widespread differential expression of miRNA genes in malignant …
Non-coding RNA
JS Mattick, IV Makunin - Human molecular genetics, 2006 - academic.oup.com
The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a
protein, but this does not mean that such RNAs do not contain information nor have function …
protein, but this does not mean that such RNAs do not contain information nor have function …
[HTML][HTML] microRNAs as oncogenes and tumor suppressors
microRNAs (miRNAs) are a new class of non-protein-coding, endogenous, small RNAs.
They are important regulatory molecules in animals and plants. miRNA regulates gene …
They are important regulatory molecules in animals and plants. miRNA regulates gene …
Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection
NJ Park, H Zhou, D Elashoff, BS Henson… - Clinical Cancer …, 2009 - AACR
Purpose: We have previously shown that a transcriptome is found in saliva and subpanels of
these mRNAs can be used as oral cancer biomarkers. In this study, we measured the …
these mRNAs can be used as oral cancer biomarkers. In this study, we measured the …
MicroRNA function in cancer: oncogene or a tumor suppressor?
SK Shenouda, SK Alahari - Cancer and metastasis reviews, 2009 - Springer
MicroRNAs (miRNAs) are small noncoding, double-stranded RNA molecules that can
mediate the expression of target genes with complementary sequences. About 5,300 human …
mediate the expression of target genes with complementary sequences. About 5,300 human …
miR-15a and miR-16-1 in cancer: discovery, function and future perspectives
MicroRNAs (miRNAs) encoded by the miR-15/16 cluster are known to act as tumor
suppressors. Expression of these miRNAs inhibits cell proliferation, promotes apoptosis of …
suppressors. Expression of these miRNAs inhibits cell proliferation, promotes apoptosis of …
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
Background MicroRNAs (miRNAs), a class of short non-coding RNAs found in many plants
and animals, often act post-transcriptionally to inhibit gene expression. Results Here we …
and animals, often act post-transcriptionally to inhibit gene expression. Results Here we …