Limonene is a monoterpene confined to the family of Rutaceae, showing several biological
properties such as antioxidant, anti-inflammatory, anticancer, antinociceptive and …

Epilepsy is one of the commonly prevailing neurological disorders. According to the reports,
it is evident that about 80% of the epileptic cases have been observed in developing …

A new series of quinazoline-4 (3 H)-ones are evaluated for anticonvulsant activity. After
intraperitoneal (ip) injection to albino mice at a dose of 100 mg/kg body weight, synthesized …

An operation friendly protocol for the synthesis of novel di (indolyl) indolin-2-ones via Cu
(OTf) 2 catalyzed bis-addition of N-allyl and N-propargyl indole with isatin was developed …

In this study, a new compound namely 1-((2-hydroxynaphthalen-1-yl) methyleneamino)-5-(4-
methybenzoyl)-4-p-tolylpyrimidin-2 (1H)-one (S2) was synthesized as a Schiff base using 1 …

A series of stiripentol (STP) analogues namely, 2-[(1E)-1-(1, 3-benzodioxol-5-yl)-4, 4-
dimethylpent-1-en-3-ylidene]-N-(aryl/H) hydrazinecarboxamides 7a–h,(±)-(5RS)-N-(aryl/H) …

Background: Heterocycles play a major role in many fields of biochemical and physiological
such as amino acids, DNA bases, vitamins, endogenous neurotransmitters, etc …

Pyrimidine itself or in different fused forms is an important chemical motif for every step of
cell life. Alongside, it exists as a key pharmacophoric part in thiamine, alloxan, orotic acid …

Two novel series of N4-(5-(2/3/4-substituted-phenyl)-1, 3, 4-oxadiazol-2-yl)-N1-(2-methyl-5-
(prop-1-en-2-yl) cyclohex-2-enylidene) semicarbazide and N4-(5-(2/3/4-substituted-phenyl) …

Sažetak There are several limited approaches to treat epilepsy in hospitals, for example,
using medicines, surgery, electrical stimulation and dietary interventions. Despite the …