HIV‐associated chronic immune activation
M Paiardini, M Müller‐Trutwin - Immunological reviews, 2013 - Wiley Online Library
Systemic chronic immune activation is considered today as the driving force of CD 4+ T‐cell
depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune …
depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune …
Natural SIV hosts: showing AIDS the door
Many species of African nonhuman primates are naturally infected with simian
immunodeficiency viruses (SIVs) in the wild and in captivity. In contrast to HIV-infected …
immunodeficiency viruses (SIVs) in the wild and in captivity. In contrast to HIV-infected …
Altered virome and bacterial microbiome in human immunodeficiency virus-associated acquired immunodeficiency syndrome
Human immunodeficiency virus (HIV) infection is associated with increased intestinal
translocation of microbial products and enteropathy as well as alterations in gut bacterial …
translocation of microbial products and enteropathy as well as alterations in gut bacterial …
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
Natural SIV infection of sooty mangabeys (SMs) is nonprogressive despite chronic virus
replication. Strikingly, it is characterized by low levels of immune activation, while …
replication. Strikingly, it is characterized by low levels of immune activation, while …
The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
While CD4+ T cell depletion is key to disease progression in people living with HIV and SIV-
infected macaques, the mechanisms underlying this depletion remain incompletely …
infected macaques, the mechanisms underlying this depletion remain incompletely …
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts
DL Sodora, JS Allan, C Apetrei, JM Brenchley… - Nature medicine, 2009 - nature.com
The design of an effective AIDS vaccine has eluded the efforts of the scientific community to
the point that alternative approaches to classic vaccine formulations have to be considered …
the point that alternative approaches to classic vaccine formulations have to be considered …
CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells
NR Klatt, E Shudo, AM Ortiz, JC Engram… - PLoS …, 2010 - journals.plos.org
While CD8+ T cells are clearly important in controlling virus replication during HIV and SIV
infections, the mechanisms underlying this antiviral effect remain poorly understood. In this …
infections, the mechanisms underlying this antiviral effect remain poorly understood. In this …
Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections
JM Brenchley, C Vinton, B Tabb, XP Hao… - Blood, the Journal of …, 2012 - ashpublications.org
Nonhuman primate natural hosts for simian immunodeficiency viruses (SIV) develop a
nonresolving chronic infection but do not develop AIDS. Mechanisms to explain the …
nonresolving chronic infection but do not develop AIDS. Mechanisms to explain the …
Th17 cell dynamics in HIV infection
NR Klatt, JM Brenchley - Current Opinion in HIV and AIDS, 2010 - journals.lww.com
Th17 cell dynamics in HIV infection : Current Opinion in HIV and AIDS Th17 cell dynamics in
HIV infection : Current Opinion in HIV and AIDS Log in or Register Subscribe to journalSubscribe …
HIV infection : Current Opinion in HIV and AIDS Log in or Register Subscribe to journalSubscribe …