Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Preoperative diagnosis and molecular characterization of gliomas with liquid biopsy and radiogenomics

C Balana, S Castañer, C Carrato, T Moran… - Frontiers in …, 2022 - frontiersin.org
Gliomas are a heterogenous group of central nervous system tumors with different outcomes
and different therapeutic needs. Glioblastoma, the most common subtype in adults, has a …

Targeted photodynamic therapy of glioblastoma mediated by platelets with photo-controlled release property

HZ Xu, TF Li, Y Ma, K Li, Q Zhang, YH Xu, YC Zhang… - Biomaterials, 2022 - Elsevier
Photodynamic therapy (PDT) has recently emerged as a promising, targeted treatment
modality for glioblastoma (GBM) which is the most vicious type of brain tumor. Successful …

Activated platelets facilitate hematogenous metastasis of breast cancer by modulating the PDGFR-β/COX-2 axis

Y Tang, C Qian, Y Zhou, C Yu, M Song, T Zhang, X Min… - IScience, 2023 - cell.com
Platelets have been widely recognized as a bona fide mediator of malignant diseases, and
they play significant roles in influencing various aspects of tumor progression. Paracrine …

Blood-based biomarkers for glioma in the context of gliomagenesis: a systematic review

H Ali, R Harting, R de Vries, M Ali, T Wurdinger… - Frontiers in …, 2021 - frontiersin.org
Background Gliomas are the most common and aggressive tumors of the central nervous
system. A robust and widely used blood-based biomarker for glioma has not yet been …

Trauma-induced coagulopathy: overview of an emerging medical problem from pathophysiology to outcomes

G Savioli, IF Ceresa, L Caneva, S Gerosa, G Ricevuti - Medicines, 2021 - mdpi.com
Coagulopathy induced by major trauma is common, affecting approximately one-third of
patients after trauma. It develops independently of iatrogenic, hypothermic, and dilutive …

The role of platelets in the regulation of tumor growth and metastasis: the mechanisms and targeted therapy

K Liao, X Zhang, J Liu, F Teng, Y He, J Cheng… - MedComm, 2023 - Wiley Online Library
Platelets are a class of pluripotent cells that, in addition to hemostasis and maintaining
vascular endothelial integrity, are also involved in tumor growth and distant metastasis. The …

Trauma coagulopathy and its outcomes

G Savioli, IF Ceresa, S Macedonio, S Gerosa… - Medicina, 2020 - mdpi.com
Background and Objectives: Trauma coagulopathy begins at the moment of trauma. This
study investigated whether coagulopathy upon arrival in the emergency room (ER) is …

Strategies, considerations, and recent advancements in the development of liquid biopsy for glioblastoma: a step towards individualized medicine in glioblastoma

MMJ Bauman, SM Bouchal, DD Monie, A Aibaidula… - Neurosurgical …, 2022 - thejns.org
OBJECTIVE Glioblastoma (GBM) is a devasting primary brain tumor with less than a 5% 5-
year survival. Treatment response assessment can be challenging because of inflammatory …

Word2vec word embedding-based artificial intelligence model in the triage of patients with suspected diagnosis of major ischemic stroke: a feasibility study

A Desai, A Zumbo, M Giordano, P Morandini… - International Journal of …, 2022 - mdpi.com
Background: The possible benefits of using semantic language models in the early
diagnosis of major ischemic stroke (MIS) based on artificial intelligence (AI) are still …