Caspase-mediated anti-apoptotic effect of ginsenoside Rg5, a main rare ginsenoside, on acetaminophen-induced hepatotoxicity in mice

Z Wang, J Hu, M Yan, J Xing, W Liu… - Journal of agricultural and …, 2017 - ACS Publications
Frequent overdose of acetaminophen (APAP) is one of the most common and important
incentives of acute hepatotoxicity. Prior to this work, our research group confirmed that black …

Lead induces structural damage, microbiota dysbiosis and cell apoptosis in the intestine of juvenile bighead carp (Hypophthalmichthys nobilis)

H Liu, S Fu, S Zhang, M Ding, A Wang - Aquaculture, 2020 - Elsevier
Lead (Pb) is an environmental pollutant that can accumulate in fish and humans. In this
study, the effects of juvenile bighead carp (Hypophthalmichthys nobilis) on the intestinal …

Carnosic acid induces apoptosis of hepatocellular carcinoma cells via ROS-mediated mitochondrial pathway

X Zhang, Y Chen, G Cai, X Li, D Wang - Chemico-Biological Interactions, 2017 - Elsevier
Carnosic acid (CA), an important bioactive phenolic diterpene mainly found in labiate plants,
exerts various biological functions, including antioxidant, anti-inflammatory, antitumor, and …

AIM2 enhances Candida albicans infection through promoting macrophage apoptosis via AKT signaling

Q Jiang, Y Chen, S Zheng, L Sui, D Yu, F Qing… - Cellular and Molecular …, 2024 - Springer
Candida albicans is among the most prevalent invasive fungal pathogens for
immunocompromised individuals and novel therapeutic approaches that involve immune …

Lysionotin induces apoptosis of hepatocellular carcinoma cells via caspase-3 mediated mitochondrial pathway

A Yang, P Zhang, Z Sun, X Liu, X Zhang, X Liu… - Chemico-Biological …, 2021 - Elsevier
Highlights•Lysionotin induces apoptosis in liver cancer cells.•Lysionotin causes the caspase-
3 mediated mitochondrial apoptosis.•Oxidative stress is involved in lysionotin-mediated …

Midpalatal Suture: Single-Cell RNA-Seq Reveals Intramembrane Ossification and Piezo2 Chondrogenic Mesenchymal Cell Involvement

L Gao, T Xu, L Zhang, Y Li, T Yan, G Yu, F Chen - Cells, 2022 - mdpi.com
The midpalatal suture is mainly responsible for the growth and development of the maxillary
and resistance to rapid maxillary expansion (RME). It is essential for clinical researchers to …

Preparation and evaluation of folate-decorated human serum albumin nanoparticles for the targeted delivery of sorafenib to enhance antihepatocarcinoma efficacy

W Gao, X Jia, J Wu, Y Song, J Yin, M Zhang… - Journal of Drug Delivery …, 2019 - Elsevier
Sorafenib is a multitarget tyrosine kinase inhibitor for the first-line treatment of hepatocellular
carcinoma (HCC). However, moderate therapeutic effects are common in the clinic …

Caffeine improves bladder function in diabetic rats via a neuroprotective effect

J Xue, Y Liu, S Zhang, L Ding… - Experimental and …, 2021 - spandidos-publications.com
Diabetic cystopathy (DCP) is one of the most common complications of diabetes mellitus
(DM). A previous study reported that caffeine may improve bladder dysfunction in rats with …

Layer dependence in strain distribution and chondrocyte damage in porcine articular cartilage exposed to excessive compressive stress loading

W Huang, M Warner, H Sasaki, KS Furukawa… - Journal of the …, 2020 - Elsevier
Exposure to excessive stress is associated with the pathogenesis of osteoarthritis, a joint
disease involved in the degeneration of articular cartilage. Mechanical properties of mature …

Infiltration and In-Tissue Polymerization of Photocross-Linked Hydrogel for Effective Fixation of Implants into Cartilage—An In Vitro Study

B Kuang, Y Yang, H Lin - ACS omega, 2019 - ACS Publications
Effective and biocompatible fixation of implants into cartilage defects has yet to be
successfully achieved.[Poly-d, l-lactic acid/polyethyleneglycol/poly-d, l-lactic acid](PDLLA …