Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

Systemic inflammation can be triggered by infection, surgery, trauma or burns. During
systemic inflammation, an overshooting immune response induces tissue damage resulting …

This review summarizes the receptor-mediated vascular activities of calcitonin gene-related
peptide (CGRP) and the structurally related peptide adrenomedullin (AM). CGRP is a 37 …

This reference presents entries on more than 3,100 agents that can cause birth defects,
including chemicals, drugs, physical factors, gene mutations, and viruses. Approximately …

The oral cavity is a unique environment in which antimicrobial peptides play a key role in
maintaining health and may have future therapeutic applications. Present evidence …

Calcitonin was discovered over 50 yr ago as a new hormone that rapidly lowers circulating
calcium levels. This effect is caused by the inhibition of calcium efflux from bone, as …

Hemodynamic responses that control blood pressure and the distribution of blood flow to
different organs are essential for survival. Shear forces generated by blood flow regulate …

Cornelia de Lange Syndrome (CdLS) is a multi-organ system birth defects disorder linked, in
at least half of cases, to heterozygous mutations in the NIPBL gene. In animals and fungi …

Background Adrenomedullin (AM) is a vasodilating peptide involved in the regulation of
circulatory homeostasis and in the pathophysiology of certain cardiovascular diseases …