Systematic review: clinical metabolomics to forecast outcomes in liver transplantation surgery

JA Attard, WB Dunn, H Mergental, DF Mirza… - Omics: a journal of …, 2019 - liebertpub.com
Liver transplantation is an effective intervention for end-stage liver disease, fulminant
hepatic failure, and early hepatocellular carcinoma. Yet, there is marked patient-to-patient …

Investigating correlations in the altered metabolic profiles of obese and diabetic subjects in a South Indian Asian population using an NMR-based metabolomic …

N Gogna, M Krishna, AM Oommen, K Dorai - Molecular BioSystems, 2015 - pubs.rsc.org
It is well known that obesity/high body mass index (BMI) plays a key role in the evolution of
insulin resistance and type-2 diabetes mellitus (T2DM). However, the exact mechanism …

Metabolomic Approach by 1H NMR Spectroscopy of Serum for the Assessment of Chronic Liver Failure in Patients with Cirrhosis

R Amathieu, P Nahon, M Triba… - Journal of proteome …, 2011 - ACS Publications
Assessment of chronic liver failure (CLF) in cirrhotic patients is needed to make therapeutic
decisions. A biological score is usually performed, using the Model for End-Stage Liver …

1H NMR Metabolomics Reveals Association of High Expression of Inositol 1, 4, 5 Trisphosphate Receptor and Metabolites in Breast Cancer Patients

A Singh, RK Sharma, M Chagtoo, G Agarwal… - PLoS …, 2017 - journals.plos.org
1H NMR is used to detect alterations in metabolites and their linkage to metabolic processes
in a number of pathological conditions including breast cancer. Inositol 1, 4, 5 trisphosphate …

[HTML][HTML] Nuclear magnetic resonance metabolomics and human liver diseases: The principles and evidence associated with protein and carbohydrate metabolism

L Le Moyec, MN Triba, P Nahon… - Biomedical …, 2017 - spandidos-publications.com
During the last decade, metabolomics has become widely used in the field of human
diseases. Numerous studies have demonstrated that this is a powerful technique for …

Serum 1H-NMR metabolomic fingerprints of acute-on-chronic liver failure in intensive care unit patients with alcoholic cirrhosis

R Amathieu, MN Triba, P Nahon, N Bouchemal… - Plos one, 2014 - journals.plos.org
Introduction Acute-on-chronic liver failure is characterized by acute deterioration of liver
function in patients with compensated or decompensated, but stable, cirrhosis. However …

1H NMR spectroscopy analysis of metabolites in the kidneys provides new insight into pathophysiological mechanisms: applications for treatment with Cordyceps …

F Zhong, X Liu, Q Zhou, X Hao, Y Lu… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. The number of patients with chronic kidney disease (CKD) is continuously
growing worldwide. Treatment with traditional Chinese medicine might slow the progression …

A multimodal pipeline using NMR spectroscopy and MALDI‐TOF mass spectrometry imaging from the same tissue sample

CM Tressler, V Ayyappan, S Nakuchima… - NMR in …, 2023 - Wiley Online Library
NMR spectroscopy and matrix assisted laser desorption ionization mass spectrometry
imaging (MALDI MSI) are both commonly used to detect large numbers of metabolites and …

A lipidomics study reveals lipid signatures associated with early allograft dysfunction in living donor liver transplantation

HI Tsai, CJ Lo, CW Zheng, CW Lee, WC Lee… - Journal of Clinical …, 2018 - mdpi.com
Liver transplantation has become the ultimate treatment for patients with end stage liver
disease. However, early allograft dysfunction (EAD) has been associated with allograft loss …

Metabolic profiling of human lung injury by 1H high-resolution nuclear magnetic resonance spectroscopy of blood serum

C Singh, RK Rai, A Azim, N Sinha, A Ahmed, K Singh… - Metabolomics, 2015 - Springer
Acute respiratory distress syndrome (ARDS) contributes substantially to mortality and
morbidity in USA and worldwide. Due to limitations in early diagnostics of ARDS by classical …