Genetic and epigenetic etiology of inflammatory bowel disease: An update

S Jarmakiewicz-Czaja, M Zielińska, A Sokal, R Filip - Genes, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and
remission of the disease. The etiology of IBD is not fully understood. Many studies point to …

miRNA-based potential biomarkers and new molecular insights in ulcerative colitis

J Zhou, J Liu, Y Gao, L Shen, S Li… - Frontiers in Pharmacology, 2021 - frontiersin.org
Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease, which usually
manifests as abdominal pain, diarrhea and hematochezia. The disease often recurs and is …

New insights into the epigenetic regulation of inflammatory bowel disease

J Xu, H Xu, M Yang, Y Liang, Q Peng… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the colonic mucosa.
Environmental factors, genetics, intestinal microbiota, and the immune system are all …

CircHIPK3 regulates vascular smooth muscle cell calcification via the miR-106a-5p/MFN2 axis

WB Zhang, YF Qi, ZX Xiao, H Chen, SH Liu… - Journal of …, 2022 - Springer
Atherosclerosis is the most common arterial disease and is closely related to vascular
calcification. CircHIPK3 has been implicated in atherosclerosis development, but the …

FtMt promotes glioma tumorigenesis and angiogenesis via lncRNA SNHG1/miR-9-5p axis

S Mi, J Du, J Liu, K Hou, H Ji, S Ma, Y Ba, L Chen… - Cellular …, 2020 - Elsevier
Objective This study is to investigate the effects and the mechanisms of mitochondrial ferritin
(FtMt) on the glioma tumorigenesis and angiogenesis. Methods FtMt expression was …

microRNA-25-3p suppresses osteogenic differentiation of BMSCs in patients with osteoporosis by targeting ITGB3

D Yu, Z Li, J Cao, F Shen, G Wei - Acta Histochemica, 2022 - Elsevier
This study was conducted to investigate the impact of the microRNA (miR)-25–3p/ITGB3 axis
on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) from …

The role and mechanisms of miRNA in neonatal necrotizing enterocolitis

L Cai, D Lai, J Gao, H Wu, B Shi, H Ji, J Tou - Frontiers in Pediatrics, 2022 - frontiersin.org
Neonatal necrotizing enterocolitis (NEC), the most significant causes of neonatal mortality, is
a disease of acute intestinal inflammation. At present, it is not clear exactly how the disease …

MicroRNA-92a-3p-mediated inhibition of BCL11A upregulates γ-globin expression and inhibits oxidative stress and apoptosis in erythroid precursor cells

H Li, R Lin, H Li, R Ou, K Wang, J Lin, C Li - Hematology, 2022 - Taylor & Francis
Objective This study attempted to investigate miR-92a-3p expression in peripheral blood of
patients with severe β-thalassemia, and the effect and action mechanism of miR-92a-3p on γ …

Argonaute1 and Gawky Are Required for the Development and Reproduction of Melon fly, Zeugodacus cucurbitae

M Jamil, S Ahmad, Y Ran, S Ma, F Cao, X Lin… - Frontiers in …, 2022 - frontiersin.org
Argonaute family genes encode a highly conserved group of proteins that have been
associated with RNA silencing in both animals and plants. This study investigates the …

Processing body (P-body) and its mediators in cancer

B Nsengimana, FA Khan, EE Ngowi, X Zhou… - Molecular and cellular …, 2022 - Springer
In recent years, processing bodies (P-bodies) formed by liquid–liquid phase separation,
have attracted growing scientific attention due to their involvement in numerous cellular …