[HTML][HTML] Rosmarinic acid-From bench to valuable applications in food industry

AS Marchev, LV Vasileva, KM Amirova… - Trends in Food Science …, 2021 - Elsevier
Background Rosmarinic acid (RA) is widely distributed in plant species of Lamiaceae and
Boraginaceae families, among others. Structurally RA is an ester of caffeic acid and 3, 4 …

Caffeic acid on metabolic syndrome: A review

NN Muhammad Abdul Kadar, F Ahmad, SL Teoh… - Molecules, 2021 - mdpi.com
Metabolic syndrome (MetS) is a constellation of risk factors that may lead to a more sinister
disease. Raised blood pressure, dyslipidemia in the form of elevated triglycerides and …

Rosmarinic acid restores colonic mucus secretion in colitis mice by regulating gut microbiota-derived metabolites and the activation of inflammasomes

Q Wang, K Xu, X Cai, C Wang, Y Cao… - Journal of Agricultural …, 2023 - ACS Publications
Maintaining a steady state of mucus barrier is an important potential target for polyphenol to
exert its anticolitis activity. This study elucidates the pivotal role of polyphenol rosmaric acid …

[HTML][HTML] Rosmarinic acid attenuates obesity and obesity-related inflammation in human adipocytes

LV Vasileva, MS Savova, D Tews, M Wabitsch… - Food and Chemical …, 2021 - Elsevier
Chronic low-grade inflammation is a hallmark of obesity and its related metabolic disorders.
At the same time signaling from pro-inflammatory factors such as transforming growth factor …

Mechanistic understanding from molecular dynamics in pharmaceutical research 2: lipid membrane in drug design

T Róg, M Girych, A Bunker - Pharmaceuticals, 2021 - mdpi.com
We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …

Caffeic and chlorogenic acids synergistically activate browning program in human adipocytes: Implications of AMPK-and PPAR-mediated pathways

LV Vasileva, MS Savova, KM Amirova… - International Journal of …, 2020 - mdpi.com
Caffeic acid (CA) and chlorogenic acid (CGA) are phenolic compounds claimed to be
responsible for the metabolic effects of coffee and tea consumption. Along with their …

Electrochemical deposition of bio-inspired laccase-polydopamine films for phenolic sensors

LC Almeida, RD Correia, G Squillaci, A Morana… - Electrochimica …, 2019 - Elsevier
Hereby, a precisely controlled one-step electrode modification is presented where the
enzyme laccase is immobilized during the potentiostatic deposition of a thin polydopamine …

Designing new antitubercular isoniazid derivatives with improved reactivity and membrane trafficking abilities

CF de Faria, T Moreira, P Lopes, H Costa… - Biomedicine & …, 2021 - Elsevier
Isoniazid (INH) is one of the two most effective first-line antitubercular drugs and is still used
at the present time as a scaffold for developing new compounds to fight TB. In a previous …

Sphingolipid hydroxylation in mammals, yeast and plants–An integrated view

JT Marquês, HS Marinho, RFM de Almeida - Progress in lipid research, 2018 - Elsevier
This review is focused on sphingolipid backbone hydroxylation, a small but widespread
structural feature with profound impact on membrane biophysical properties. We start by …

Antiviral and antibacterial activity of hand sanitizer and surface disinfectant formulations

HAL Filipe, SM Fiuza, CA Henriques… - International Journal of …, 2021 - Elsevier
Emergent diseases caused by viral and bacterial infections have proven to be a current and
future challenge. The occurrence of these diseases is usually accompanied by the lack of …