Organoids are simple tissue-engineered cell-based in vitro models that recapitulate many
aspects of the complex structure and function of the corresponding in vivo tissue. They can …

In vitro cell cultures are crucial research tools for modeling human development and
diseases. Although the conventional monolayer cell cultures have been widely used in the …

Organoids are 3D in vitro culture systems derived from self-organizing stem cells. They can
recapitulate the in vivo architecture, functionality, and genetic signature of original tissues …

The in vitro organoid model is a major technological breakthrough that has already been
established as an essential tool in many basic biology and clinical applications. This near …

The tongue is a complex multifunctional organ that interacts and senses both interoceptively
and exteroceptively. Although it is easily visible to almost all of us, it is relatively …

Circadian clock-gated cell division cycles are observed from cyanobacteria to mammals via
intracellular molecular connections between these two oscillators. Here we demonstrate …

An organoid is a miniaturized and simplified in vitro model with a similar structure and
function to a real organ. In recent years, the use of organoids has increased explosively in …

Organoids are novel in vitro cell culture models that enable stem cells (including pluripotent
stem cells and adult stem cells) to grow and undergo self-organization within a three …

Taste bud cells regenerate throughout life. Taste bud maintenance depends on continuous
replacement of senescent taste cells with new ones generated by adult taste stem cells …

Oral organoids are complex 3-dimensional structures that develop from stem cells or organ-
specific progenitors through a process of self-organization and re-create architectures and …