Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Although promising therapeutics are in the pipeline, bariatric surgery (also known as
metabolic surgery) remains our most effective strategy for the treatment of obesity and type 2 …

The innate cytokine system is involved in the response to excessive food intake. In this
review, we highlight recent advances in our understanding of the physiological role of three …

Summary Elevated interleukin (IL)-1β levels, NLRP3 inflammasome activity, and systemic
inflammation are hallmarks of chronic metabolic inflammatory syndromes, but the …

Type 2 diabetes and atherosclerosis have gradually garnered great attention as
inflammatory diseases. Previously, the fact that Interleukin-1β (IL-1β) accelerates the …

Post‐bariatric hypoglycaemia (PBH) is a metabolic complication of bariatric surgery (BS),
consisting of low post‐prandial glucose levels in patients having undergone bariatric …

OBJECTIVE Postbariatric hypoglycemia affects> 50% of individuals who have undergone
Roux-en-Y gastric bypass surgery. Despite the often debilitating nature of this complication …

Increased activity of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3)
inflammasome–IL-1β pathway is observed in obesity and contributes to the development of …

Context Post-bariatric hypoglycemia (PBH) is an increasingly encountered complication of
upper gastrointestinal surgery; the prevalence of this condition is anticipated to rise given …

The rapidly evolving field of immunometabolism explores how changes in local immune
environments may affect key metabolic and cellular processes, including that of adipose …