[HTML][HTML] The versatile functions of Sox9 in development, stem cells, and human diseases

A Jo, S Denduluri, B Zhang, Z Wang, L Yin, Z Yan… - Genes & diseases, 2014 - Elsevier
The transcription factor Sox9 was first discovered in patients with campomelic dysplasia, a
haploinsufficiency disorder with skeletal deformities caused by dysregulation of Sox9 …

Meat-adaptive genes and the evolution of slower aging in humans

CE Finch, CB Stanford - The Quarterly review of biology, 2004 - journals.uchicago.edu
The chimpanzee life span is shorter than that of humans, which is consistent with a faster
schedule of aging. We consider aspects of diet that may have selected for genes that …

[图书][B] The biology of human longevity: Inflammation, nutrition, and aging in the evolution of lifespans

CE Finch - 2010 - books.google.com
Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human
Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes …

Congenital generalized hypertrichosis: the skin as a clue to complex malformation syndromes

P Pavone, AD Praticò, R Falsaperla, M Ruggieri… - Italian Journal of …, 2015 - Springer
Hypertrichosis is defined as an excessive growth in body hair beyond the normal variation
compared with individuals of the same age, race and sex and affecting areas not …

[图书][B] Mutants: on genetic variety and the human body

AM Leroi - 2005 - books.google.com
Visit Armand Marie Leroi on the web: http://armandleroi. com/index. html Stepping
effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of …

Trps1 and Its Target Gene Sox9 Regulate Epithelial Proliferation in the Developing Hair Follicle and Are Associated with Hypertrichosis

KA Fantauzzo, M Kurban, B Levy, AM Christiano - PLoS genetics, 2012 - journals.plos.org
Hereditary hypertrichoses are a group of hair overgrowth syndromes that are extremely rare
in humans. We have previously demonstrated that a position effect on TRPS1 is associated …

Genomic disorders: A window into human gene and genome evolution

CMB Carvalho, F Zhang… - Proceedings of the …, 2010 - National Acad Sciences
Gene duplications alter the genetic constitution of organisms and can be a driving force of
molecular evolution in humans and the great apes. In this context, the study of genomic …

Mutations in the Cholesterol Transporter Gene ABCA5 Are Associated with Excessive Hair Overgrowth

GM DeStefano, M Kurban, K Anyane-Yeboa… - PLoS …, 2014 - journals.plos.org
Inherited hypertrichoses are rare syndromes characterized by excessive hair growth that
does not result from androgen stimulation, and are often associated with additional …

X-linked congenital hypertrichosis syndrome is associated with interchromosomal insertions mediated by a human-specific palindrome near SOX3

H Zhu, D Shang, M Sun, S Choi, Q Liu, J Hao… - The American Journal of …, 2011 - cell.com
X-linked congenital generalized hypertrichosis (CGH), an extremely rare condition
characterized by universal overgrowth of terminal hair, was first mapped to chromosome …

Copy-number mutations on chromosome 17q24. 2-q24. 3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia

M Sun, N Li, W Dong, Z Chen, Q Liu, Y Xu, G He… - The American Journal of …, 2009 - cell.com
Congenital generalized hypertrichosis terminalis (CGHT) is a rare condition characterized
by universal excessive growth of pigmented terminal hairs and often accompanied with …